Purified recombinant Human LAMP1

This recombinant monoclonal antibody can detects endogenous levels of LAMP1 protein.

LAMP1

Lysosome-associated membrane glycoprotein 1 (LAMP-1) (Lysosome-associated membrane protein 1) (CD107 antigen-like family member A) (CD antigen CD107a)

LAMP1 ;
Lysosome-associated membrane glycoprotein 1 ;
LAMP-1 ;
Lysosome-associated membrane protein 1 ;
CD107 antigen-like family member A ;
CD107a

The protein encoded byThis gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq, Jul 2008]

Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis.,PTM:O- and N-glycosylated; some of the 18 N-linked glycans are polylactosaminoglycans.,similarity:Belongs to the LAMP family.,subcellular location:This protein shuttles between lysosomes, endosomes, and the plasma membrane.,

Cell membrane ; Single-pass type I membrane protein . Endosome membrane; Single-pass type I membrane protein . Lysosome membrane ; Single-pass type I membrane protein . Late endosome membrane ; Single-pass type I membrane protein . Cytolytic granule membrane ; Single-pass type I membrane protein . This protein shuttles between lysosomes, endosomes, and the plasma membrane (By similarity). Colocalizes with OSBPL1A at the late endosome (PubMed:16176980). .

>>EGFR tyrosine kinase inhibitor resistance ;
>>Endocrine resistance ;
>>Platinum drug resistance ;
>>MAPK signaling pathway ;
>>ErbB signaling pathway ;
>>Calcium signaling pathway ;
>>HIF-1 signaling pathway ;
>>PI3K-Akt signaling pathway ;
>>Focal adhesion ;
>>Adherens junction ;
>>Tight junction ;
>>Pathways in cancer ;
>>Proteoglycans in cancer ;
>>MicroRNAs in cancer ;
>>Pancreatic cancer ;
>>Endometrial cancer ;
>>Prostate cancer ;
>>Bladder cancer ;
>>Non-small cell lung cancer ;
>>Breast cancer ;
>>Gastric cancer ;
>>Central carbon metabolism in cancer