The protein encoded byThis gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form ofThis protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found forThis gene. [provided by RefSeq, Oct 2011]
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Function:
May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation.,online information:CD83 antigen,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Monomer.,tissue specificity:Expressed by activated lymphocytes, Langerhans cells and interdigitating reticulum cells.,