Catalog: YA0064
Size
Price
Status
Qty.
200μg
$600.00
3 weeks
0
100μg
$340.00
3 weeks
0
40μg
$190.00
3 weeks
0
Add to cart
Collected
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Main Information
Target
CD223/LAG-3
Reactivity
Human
Applications
ELISA
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
ELISA 1:5000-100000
Formulation
Phosphate-buffered solution
Source
Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
Specificity
This recombinant monoclonal antibody can detects endogenous levels of CD223/LAG-3 protein.
Purification
Recombinant Expression and Affinity purified
Storage
-15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Concentration
Please check the information on the tube
Modification
Unmodified
Clone Number
PN0547
Related Products
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Goat Anti Mouse IgG(H+L) (HRP)
RS0001
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Antigen&Target Information
Immunogen:
Purified recombinant Human CD223
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Specificity:
This recombinant monoclonal antibody can detects endogenous levels of CD223/LAG-3 protein.
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Gene Name:
LAG3 FDC
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Protein Name:
Lymphocyte activation gene 3 protein (LAG-3) (CD antigen CD223) [Cleaved into: Secreted lymphocyte activation gene 3 protein (sLAG-3)]
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Other Name:
LAG3 ;
FDC ;
Lymphocyte activation gene 3 protein ;
LAG-3 ;
Protein FDC ;
CD223 ;
CD223 nanobody ;
LAG-3 nanobody
FDC ;
Lymphocyte activation gene 3 protein ;
LAG-3 ;
Protein FDC ;
CD223 ;
CD223 nanobody ;
LAG-3 nanobody
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Background:
Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. [provided by RefSeq, Jul 2008]
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Function:
Involved in lymphocyte activation. Binds to HLA class-II antigens.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:On cell surface of activated NK and T-lymphocytes.,
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Cellular Localization:
[Lymphocyte activation gene 3 protein]: Cell membrane ; Single-pass type I membrane protein .; [Secreted lymphocyte activation gene 3 protein]: Secreted . Produced following cleavage of the main chain. .
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Signaling Pathway
Cellular Processes >> Cell growth and death >> Apoptosis
Human Diseases >> Cancer: overview >> Pathways in cancer
Environmental Information Processing >> Signal transduction >> JAK-STAT signaling pathway
Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction
Reference Citation({{totalcount}})
Catalog: YA0064
Size
Price
Status
Qty.
200μg
$600.00
3 weeks
0
100μg
$340.00
3 weeks
0
40μg
$190.00
3 weeks
0
Add to cart
Collected
Collect
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