Catalog: YM960330
Size
Price
Status
Qty.
200μL
$600.00
3 weeks
0
100μL
$340.00
3 weeks
0
40μL
$190.00
3 weeks
0
Add to cart
Collected
Collect
Main Information
Target
OCT1
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ELISA
MW
77kD (Calculated)
90kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000
Formulation
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Specificity
Endogenous
Purification
Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
Storage
-15°C to -25°C/1 year (Do not lower than -25°C)
MW(Calculated)
77kD
MW(Observed)
90kD
Modification
Unmodified
Clonality
Monoclonal
Clone Number
PT2040R
Isotype
IgG, Kappa
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Antigen&Target Information
Immunogen:
The specific immunogen used to produce this antibody is proprietary information.
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Specificity:
Endogenous
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Gene Name:
POU2F1
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Protein Name:
POU domain class 2 transcription factor 1
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Other Name:
POU2F1 ;
OCT1 ;
OTF1 ;
POU domain ;
class 2,transcription factor 1 ;
NF-A1 ;
Octamer-binding protein 1 ;
Oct-1 ;
Octamer-binding transcription factor 1 ;
OTF-1
OCT1 ;
OTF1 ;
POU domain ;
class 2,transcription factor 1 ;
NF-A1 ;
Octamer-binding protein 1 ;
Oct-1 ;
Octamer-binding transcription factor 1 ;
OTF-1
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Background:
The OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al. , 1993 [PubMed 8314572]) . Members of this family contain the POU domain , a 160-amino acid region necessary for DNA binding to the octameric sequence ATGCAAAT.[supplied by OMIM , Jul 2010] ,
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Function:
Function:Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1 , AR and PGR. ,PTM:Phosphorylated by PRKDC. ,similarity:Belongs to the POU transcription factor family. Class-2 subfamily. ,similarity:Contains 1 homeobox DNA-binding domain. ,similarity:Contains 1 POU-specific domain. ,subunit:Interacts with NR3C1 , AR , PGR and HCFC1. ,tissue specificity:Ubiquitous. Isoform 2 is lymphocyte-specific. ,
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Cellular Localization:
Nucleus.
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Tissue Expression:
Research Areas:
>>Herpes simplex virus 1 infection ;
>>Lipid and atherosclerosis
>>Lipid and atherosclerosis
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Reference Citation({{totalcount}})
Catalog: YM960330
Size
Price
Status
Qty.
200μL
$600.00
3 weeks
0
100μL
$340.00
3 weeks
0
40μL
$190.00
3 weeks
0
Add to cart
Collected
Collect
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