Catalog: YM960465
Size
Price
Status
Qty.
200μL
$600.00
3 weeks
0
100μL
$340.00
3 weeks
0
40μL
$190.00
3 weeks
0
Add to cart
Collected
Collect
Main Information
Target
BAG2
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IF, ELISA
MW
24kD (Calculated)
23kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000
Formulation
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Specificity
Endogenous
Purification
Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
Storage
-15°C to -25°C/1 year (Do not lower than -25°C)
MW(Calculated)
24kD
MW(Observed)
23kD
Modification
Unmodified
Clonality
Monoclonal
Clone Number
PT2109R
Isotype
IgG, Kappa
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Antigen&Target Information
Immunogen:
The specific immunogen used to produce this antibody is proprietary information.
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Specificity:
Endogenous
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Gene Name:
BAG2
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Protein Name:
BAG family molecular chaperone regulator 2 (BAG-2) (Bcl-2-associated athanogene 2)
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Background:
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1 , BAG2 , and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq , Jul 2008] ,
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Function:
Function:Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. ,similarity:Contains 1 BAG domain. ,subunit:Binds to the ATPase domain of HSP70/HSC chaperones. ,
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Cellular Localization:
cytosol ,
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Tissue Expression:
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Research Areas:
>>Protein processing in endoplasmic reticulum
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YM960465
Size
Price
Status
Qty.
200μL
$600.00
3 weeks
0
100μL
$340.00
3 weeks
0
40μL
$190.00
3 weeks
0
Add to cart
Collected
Collect
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