VAV2

Guanine nucleotide exchange factor VAV2 ;
VAV-2 ;

function:Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases. ,similarity:Contains 1 CH (calponin-homology) domain. ,similarity:Contains 1 DH (DBL-homology) domain. ,similarity:Contains 1 PH domain. ,similarity:Contains 1 phorbol-ester/DAG-type zinc finger. ,similarity:Contains 1 SH2 domain. ,similarity:Contains 2 SH3 domains. ,tissue specificity:Widely expressed. ,

apoptosis , induction of apoptosis , cell motion , intracellular signaling cascade , small GTPase mediated signal transduction , cell death , induction of apoptosis by extracellular signals , regulation of cell death , positive regulation of cell death , programmed cell death , induction of programmed cell death , death , cell migration , regulation of lipid metabolic process , regulation of phosphate metabolic process , cell projection organization , cell projection assembly ,lamellipodium assembly , positive regulation of kinase activity , regulation of Rho protein signal transduction , regulation of phosphorylation , regulation of apoptosis , positive regulation of apoptosis , regulation of programmed cell death ,positive regulation of programmed cell death , positive regulation of catalytic activity , regulation of kinase activity ,regulation of lipid kinase activity , regulation of phosphoinositide 3-kinase activity , positive regulation of phosphoinositide 3-kinase activity , positive regulation of molecular function , positive regulation of lipid metabolic process , regulation of Ras protein signal transduction , cell motility , regulation of small GTPase mediated signal transduction , regulation of phosphorus metabolic process , regulation of transferase activity , positive regulation of transferase activity , localization of cell ,