SNAI 1 (Phospho Ser246) Cell-Based Colorimetric ELISA Kit

-KA1535C

Catalog: KA1535C
Size
Price
Status
Qty.
96well
$470.00
2 weeks

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Main Information
Reactivity

Human, Mouse

Applications

ELISA

Conjugate/Modification


phosphate

Detailed Information
Storage
2-8°C/6 months,Ship by ice bag
Modification
phosphate
Detection Method
Colorimetric
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ELISA Kits
SNAI 1 (Phospho Ser246) Cell-Based Colorimetric ELISA Kit
KA1535C

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Antigen&Target Information
Gene Name:
SNAI1
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Other Name:
Zinc finger protein SNAI1 ;
Protein snail homolog 1 ;
Protein sna ;
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Database Link:
Organism Gene ID SwissProt
Human 6615; O95863;
Mouse 20613; Q02085;
Background:
snail family transcriptional repressor 1 (SNAI1) Homo sapiens The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein , and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. [provided by RefSeq , Jul 2008] ,
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Function:
Function:Seems to be involved in embryonic mesoderm formation. Binds to 3 E-boxes of the E-cadherin gene promoter and represses its transcription. ,similarity:Belongs to the snail C2H2-type zinc-finger protein family. ,similarity:Contains 4 C2H2-type zinc fingers. ,tissue specificity:Expressed in a variety of tissues with the highest expression in kidney. ,
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Cellular Localization:
Nucleus . Cytoplasm . Once phosphorylated (probably on Ser-107 , Ser-111 , Ser-115 and Ser-119) it is exported from the nucleus to the cytoplasm where subsequent phosphorylation of the destruction motif and ubiquitination involving BTRC occurs. .
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Catalog: KA1535C
Size
Price
Status
Qty.
96well
$470.00
2 weeks

0

Add to cart

Collected

Collect

Customized Service

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