Catalog: YD3038
Size
Price
Status
Qty.
500μg
$1,356.00
3 weeks
0
50μg
$272.00
3 weeks
0
5μg
$52.00
3 weeks
0
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Detailed Information
Formulation
Phosphate-buffered solution
Source
Mammalian cells
Purity
>90% as determined by SDS-PAGE
Storage
-15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Antigen&Target Information
Sequence:
Amino acid:495-728,with human FC tag.
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Gene Name:
HGF
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Protein Name:
Hepatocyte growth factor (Hepatopoietin-A) (Scatter factor) (SF) [Cleaved into: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain]
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Other Name:
Hepatocyte growth factor ;
Hepatopoietin-A ;
Scatter factor ;
SF ;
HGF ;
HPTA ;
Hepatopoietin-A ;
Scatter factor ;
SF ;
HGF ;
HPTA ;
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Function:
Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types (PubMed:20624990). Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization (PubMed:15167892, PubMed:20977675). Activates MAPK signaling following TMPRSS13 cleavage and activation (PubMed:20977675).
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Signaling Pathway
Cellular Processes >> Cellular community - eukaryotes >> Focal adhesion
Human Diseases >> Cancer: overview >> Pathways in cancer
Human Diseases >> Cancer: specific types >> Hepatocellular carcinoma
Human Diseases >> Cancer: specific types >> Gastric cancer
Human Diseases >> Cancer: specific types >> Melanoma
Human Diseases >> Cancer: specific types >> Renal cell carcinoma
Human Diseases >> Cancer: specific types >> Non-small cell lung cancer
Environmental Information Processing >> Signal transduction >> MAPK signaling pathway
Environmental Information Processing >> Signal transduction >> Ras signaling pathway
Environmental Information Processing >> Signal transduction >> Rap1 signaling pathway
Environmental Information Processing >> Signal transduction >> Calcium signaling pathway
Environmental Information Processing >> Signal transduction >> PI3K-Akt signaling pathway
Reference Citation({{totalcount}})
Catalog: YD3038
Size
Price
Status
Qty.
500μg
$1,356.00
3 weeks
0
50μg
$272.00
3 weeks
0
5μg
$52.00
3 weeks
0
Add to cart
Collected
Collect
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