Catalog: YD3033
Size
Price
Status
Qty.
500μg
$1,356.00
3 weeks
0
50μg
$272.00
3 weeks
0
5μg
$52.00
3 weeks
0
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Detailed Information
Formulation
Phosphate-buffered solution
Source
Mammalian cells
Purity
>90% as determined by SDS-PAGE
Storage
-15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Antigen&Target Information
Gene Name:
GATA3
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Protein Name:
Trans-acting T-cell-specific transcription factor GATA-3 (GATA-binding factor 3)
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Other Name:
Trans-acting T-cell-specific transcription factor GATA-3 ;
GATA-binding factor 3 ;
GATA3 ;
GATA-binding factor 3 ;
GATA3 ;
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Function:
Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. Positively regulates ASB2 expression (By similarity). Coordinates macrophage transcriptional activation and UCP2-dependent metabolic reprogramming in response to IL33. Upon tissue injury, acts downstream of IL33 signaling to drive differentiation of inflammation-resolving alternatively activated macrophages.
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Cellular Localization:
Nucleus.
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Tissue Expression:
T-cells and endothelial cells.
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YD3033
Size
Price
Status
Qty.
500μg
$1,356.00
3 weeks
0
50μg
$272.00
3 weeks
0
5μg
$52.00
3 weeks
0
Add to cart
Collected
Collect
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