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CD275 (B7-H2, B7-RP1, ICOSL) recombinant protein

-YD3018

Catalog: YD3018
Size
Price
Status
Qty.
500μg
$1,356.00
3 weeks

0

50μg
$272.00
3 weeks

0

5μg
$52.00
3 weeks

0

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Collected

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Main Information
Reactivity

Human,

Detailed Information
Formulation
Phosphate-buffered solution
Source
Mammalian cells
Purity
>90% as determined by SDS-PAGE
Storage
-15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Antigen&Target Information
Sequence:
Amino acid:19-256,with human FC tag.
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Gene Name:
ICOSLG
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Protein Name:
ICOS ligand (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (CD antigen CD275)
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Other Name:
ICOS ligand ;
B7 homolog 2 ;
B7-H2 ;
B7-like protein Gl50 ;
B7-related protein 1 ;
B7RP-1 ;
CD antigen CD275 ;
ICOSLG ;
B7H2 ;
B7RP1 ;
ICOSL ;
KIAA0653 ;
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Database Link:
Organism Gene ID SwissProt
Human 102723996; O75144;
Function:
Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity).
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Cellular Localization:
Cell membrane ; Single-pass type I membrane protein .
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Tissue Expression:
Isoform 1 is widely expressed (brain, heart, kidney, liver, lung, pancreas, placenta, skeletal muscle, bone marrow, colon, ovary, prostate, testis, lymph nodes, leukocytes, spleen, thymus and tonsil), while isoform 2 is detected only in lymph nodes, leukocytes and spleen. Expressed on activated monocytes and dendritic cells.
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Catalog: YD3018
Size
Price
Status
Qty.
500μg
$1,356.00
3 weeks

0

50μg
$272.00
3 weeks

0

5μg
$52.00
3 weeks

0

Add to cart

Collected

Collect

Customized Service

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