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Detailed Information
Formulation
Phosphate-buffered solution
Source
Mammalian cells
Purity
>90% as determined by SDS-PAGE
Storage
-15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Antigen&Target Information
Sequence:
Amino acid:1-78,with human FC tag.
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Gene Name:
TNFRSF13C
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Protein Name:
Tumor necrosis factor receptor superfamily member 13C (B-cell-activating factor receptor) (BAFF receptor) (BAFF-R) (BLyS receptor 3) (CD antigen CD268)
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Other Name:
Tumor necrosis factor receptor superfamily member 13C ;
B-cell-activating factor receptor ;
BAFF receptor ;
BAFF-R ;
BLyS receptor 3 ;
CD antigen CD268 ;
TNFRSF13C ;
BAFFR ;
BR3 ;
B-cell-activating factor receptor ;
BAFF receptor ;
BAFF-R ;
BLyS receptor 3 ;
CD antigen CD268 ;
TNFRSF13C ;
BAFFR ;
BR3 ;
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Function:
B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response.
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Cellular Localization:
Membrane ; Single-pass type III membrane protein .
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Tissue Expression:
Highly expressed in spleen and lymph node, and in resting B-cells. Detected at lower levels in activated B-cells, resting CD4+ T-cells, in thymus and peripheral blood leukocytes.
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Signaling Pathway
Organismal Systems >> Immune system >> Intestinal immune network for IgA production Human Diseases >> Immune disease >> Primary immunodeficiency Environmental Information Processing >> Signal transduction >> NF-kappa B signaling pathway Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction
Catalog: YD3010
Size
Price
Status
Qty.
500μg
$1,356.00
3 weeks
0
50μg
$272.00
3 weeks
0
5μg
$52.00
3 weeks
0
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