Catalog: YD3003
Size
Price
Status
Qty.
500μg
$1,356.00
3 weeks
0
50μg
$272.00
3 weeks
0
5μg
$52.00
3 weeks
0
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Detailed Information
Formulation
Phosphate-buffered solution
Source
Mammalian cells
Purity
>90% as determined by SDS-PAGE
Storage
-15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Antigen&Target Information
Sequence:
Amino acid:1-37,with human FC tag.
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Gene Name:
C5AR1
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Protein Name:
C5a anaphylatoxin chemotactic receptor 1 (C5a anaphylatoxin chemotactic receptor) (C5a-R) (C5aR) (CD antigen CD88)
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Other Name:
C5a anaphylatoxin chemotactic receptor 1 ;
C5a anaphylatoxin chemotactic receptor ;
C5a-R ;
C5aR ;
CD antigen CD88 ;
C5AR1 ;
C5AR ;
C5R1 ;
C5a anaphylatoxin chemotactic receptor ;
C5a-R ;
C5aR ;
CD antigen CD88 ;
C5AR1 ;
C5AR ;
C5R1 ;
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Function:
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:10636859, PubMed:15153520, PubMed:1847994, PubMed:29300009, PubMed:7622471, PubMed:8182049, PubMed:9553099). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:7622471, PubMed:8182049, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520).
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Cellular Localization:
Cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle . Note=Phosphorylated C5aR colocalizes with ARRB1 and ARRB2 in cytoplasmic vesicles. .
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YD3003
Size
Price
Status
Qty.
500μg
$1,356.00
3 weeks
0
50μg
$272.00
3 weeks
0
5μg
$52.00
3 weeks
0
Add to cart
Collected
Collect
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