Catalog: IHCM6693
Size
Price
Status
Qty.
100mL
$2,960.00
3 weeks
0
10mL
$356.00
3 weeks
0
3mL
$156.00
3 weeks
0
Add to cart
Collected
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Main Information
Target
PAX-5
Host Species
Mouse
Reactivity
Human, Mouse, Rat
Applications
IHC
Conjugate/Modification
Unmodified
Detailed Information
Specificity
This antibody detects endogenous levels of PAX-5 protein.
Purification
The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
Storage
2°C to 8°C/1 year,Ship by ice bag
Modification
Unmodified
Clonality
Monoclonal
Clone Number
PTR1332
Isotype
IgG
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Antigen&Target Information
Immunogen:
Synthesized peptide derived from human PAX-5 AA range:300-383
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Specificity:
This antibody detects endogenous levels of PAX-5 protein.
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Gene Name:
PAX5
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Protein Name:
PAX-5
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Other Name:
Paired box protein Pax-5 ;
B-cell-specific transcription factor ;
BSAP ;
B-cell-specific transcription factor ;
BSAP ;
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Function:
developmental stage:Expressed at early B-cell differentiation, in the developing CNS and in adult testis.,Disease:A chromosomal aberration involving PAX5 is a cause of acute lymphoblastic leukemia. Translocation t(9;18)(p13;q11.2) with ZNF521. Translocation t(9;3)(p13;p14.1) with FOXP1. Translocation t(9;12)(p13;p13) with ETV6.,Function:May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene.,PTM:O-glycosylated.,similarity:Contains 1 paired domain.,subunit:Interacts with DAXX (By similarity). Binds DNA as a monomer. Binds TLE4.,
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Cellular Localization:
Nuclear
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Reference Citation({{totalcount}})
Catalog: IHCM6693
Size
Price
Status
Qty.
100mL
$2,960.00
3 weeks
0
10mL
$356.00
3 weeks
0
3mL
$156.00
3 weeks
0
Add to cart
Collected
Collect
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