Catalog: KA1470C
Size
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Status
Qty.
96well
$470.00
2 weeks
0
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Main Information
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
phosphate
Detailed Information
Storage
2-8°C/6 months,Ship by ice bag
Modification
phosphate
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
PRKAR2B
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Other Name:
cAMP-dependent protein kinase type II-beta regulatory subunit
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Database Link:
Background:
function:Type II regulatory chains mediate membrane association by binding to anchoring proteins , including the MAP2 kinase. ,PTM:Phosphorylated by the activated catalytic chain. ,similarity:Belongs to the cAMP-dependent kinase regulatory chain family. ,similarity:Contains 2 cyclic nucleotide-binding domains. ,subunit:The inactive form of the enzyme is composed of two regulatory chains and two catalytic chains. Activation by cAMP produces two active catalytic monomers and a regulatory dimer that binds four cAMP molecules. ,tissue specificity:Four types of regulatory chains are found: I-alpha , I-beta , II-alpha , and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible. ,
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Function:
regulation of protein amino acid phosphorylation , fatty acid metabolic process , intracellular signaling cascade ,behavior , learning or memory , learning , response to endogenous stimulus , response to hormone stimulus , hormone-mediated signaling , response to organic substance , regulation of phosphate metabolic process , regulation of protein modification process , activation of protein kinase activity , regulation of cellular protein metabolic process , cellular response to hormone stimulus , positive regulation of kinase activity , activation of protein kinase A activity , regulation of phosphorylation , positive regulation of catalytic activity , regulation of kinase activity , positive regulation of molecular function , regulation of protein kinase activity , positive regulation of protein kinase activity , neurological system process , cognition , regulation of phosphorus metabolic process , regulation of transferase activity , positive regulation of transferase activity ,
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Cellular Localization:
Cytoplasm . Cell membrane . Colocalizes with PJA2 in the cytoplasm and at the cell membrane.
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Signaling Pathway
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Catalog: KA1470C
Size
Price
Status
Qty.
96well
$470.00
2 weeks
0
Add to cart
Collected
Collect
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