CLDN7 CEPTRL2 CPETRL2

Claudin-7

CEPTR L2 ;
CEPTRL 2 ;
CEPTRL2 ;
Claudin 1 ;
Claudin 7 ;
Claudin 9 ;
Claudin-7 ;
Claudin1 ;
Claudin7 ;
Claudin9 ;
CLD7_HUMAN ;
CLDN 7 ;
CLDN-7 ;
CLDN7 ;
Clostridium perfringens enterotoxin receptor like 2 ;
CPETR L2 ;
CPETRL 2 ;
CPETRL2 ;
Hs.84359

function:Plays a major role in tight junction-specific obliteration of the intercellular space. ,induction:By androgens. ,similarity:Belongs to the claudin family. ,subunit:Directly interacts with TJP1/ZO-1 , TJP2/ZO-2 and TJP3/ZO-3. ,tissue specificity:Expressed in kidney , lung and prostate. Isoform 1 seems to be predominant , except in some normal prostate samples , where isoform 2 is the major form. Down-regulated in breast cancers , including ductal carcinoma in situ (DCIS) , lobular carcinoma in situ (LCIS) and invasive ductal carcinoma (IDC) (at protein level) , as well as in several cancer cell lines. Loss of expression correlates with histological grade , occurring predominantly in high-grade lesions. ,

cell adhesion , cell-cell adhesion , calcium-independent cell-cell adhesion , biological adhesion ,

Cell membrane ; Multi-pass membrane protein . Basolateral cell membrane . Cell junction , tight junction . Co-localizes with EPCAM at the basolateral cell membrane and tight junction. .