Catalog: KA1450C
Size
Price
Status
Qty.
96well
$470.00
2 weeks
0
Add to cart
Collected
Collect
Main Information
Reactivity
Human, Mouse
Applications
ELISA
Conjugate/Modification
phosphate
Detailed Information
Storage
2-8°C/6 months,Ship by ice bag
Modification
phosphate
Detection Method
Colorimetric
Related Products
Primary Antibodies
Dematin Rabbit pAb
YT1325
More→
Primary Antibodies
Dematin (Phospho Ser403) Rabbit pAb
YP0737
More→
ELISA Kits
Total Dematin Cell-Based Colorimetric ELISA Kit
KA4075C
More→
ELISA Kits
Dematin (Phospho Ser403) Cell-Based Colorimetric ELISA Kit
KA1450C
More→
Antigen&Target Information
Gene Name:
EPB49
show all
Other Name:
Dematin ;
Erythrocyte membrane protein band 4.9 ;
Erythrocyte membrane protein band 4.9 ;
show all
Background:
domain:Consists of a large core fragment , the amino-terminal portion , and a small headpiece , the C-terminal portion. The headpiece can bind but cannot bundle actin filaments. ,domain:Contains at least two actin-binding sites , one in the headpiece domain and one in the amino-terminal portion. ,function:Actin-bundling protein. May function in mitogen-activated protein kinase pathway. ,PTM:Actin-bundling activity is abolished upon phosphorylation by cAMP-dependent protein kinase. ,PTM:The N-terminus is blocked. ,similarity:Belongs to the villin/gelsolin family. ,similarity:Contains 1 HP (headpiece) domain. ,subunit:Exists in solution as a trimer of two short isoforms and one long isoform linked by disulfide bonds (Probable) . Interacts with RASGRF2. ,tissue specificity:Heart , brain , lung , skeletal muscle , and kidney. ,
show all
Function:
cytoskeleton organization , actin filament organization , regulation of actin polymerization or depolymerization , negative regulation of organelle organization , actin filament-based process , actin cytoskeleton organization , regulation of actin filament length , regulation of actin filament polymerization , regulation of actin filament depolymerization , negative regulation of actin filament depolymerization , negative regulation of actin filament polymerization , negative regulation of protein complex assembly , regulation of protein polymerization , negative regulation of protein polymerization ,regulation of cellular component size , regulation of actin cytoskeleton organization , regulation of actin filament-based process , regulation of organelle organization , negative regulation of protein complex disassembly , regulation of protein complex disassembly , regulation of protein complex assembly , regulation of cellular component biogenesis ,actin filament bundle formation , negative regulation of cellular component organization , regulation of cytoskeleton organization , negative regulation of cytoskeleton organization , actin filament capping ,
show all
Cellular Localization:
Cytoplasm. Cytoplasm , cytosol. Cytoplasm , perinuclear region . Cytoplasm , cytoskeleton. Cell membrane. Membrane . Endomembrane system. Cell projection . Localized at the spectrin-actin junction of erythrocyte plasma membrane. Localized to intracellular membranes and the cytoskeletal network. Localized at intracellular membrane-bounded organelle compartment in platelets that likely represent the dense tubular network membrane. Detected at the cell membrane and at the parasitophorous vacuole in malaria-infected erythrocytes at late stages of plasmodium berghei or falciparum development.
show all
Tissue Expression:
Reference Citation({{totalcount}})
Catalog: KA1450C
Size
Price
Status
Qty.
96well
$470.00
2 weeks
0
Add to cart
Collected
Collect
Recently Viewed Products
Clear allPRODUCTS
CUSTOMIZED
ABOUT US
Toggle night Mode
{{pinfoXq.title || ''}}
Catalog: {{pinfoXq.catalog || ''}}
Filter：
All
{{item.name}}
{{pinfo.title}}
-{{pinfo.catalog}}
Main Information
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
Product {{index}}/{{pcount}}
Prev
Next
{{pvTitle}}
Scroll wheel zooms the picture
{{pvDescr}}