Catalog: KA1305C
Size
Price
Status
Qty.
96well
$470.00
2 weeks
0
Add to cart
Collected
Collect
Main Information
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
phosphate
Detailed Information
Storage
2-8°C/6 months,Ship by ice bag
Modification
phosphate
Detection Method
Colorimetric
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Primary Antibodies
MYPT1 Rabbit pAb
YT2955
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Primary Antibodies
MYPT1 (Phospho Thr696) Rabbit pAb
YP1131
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Primary Antibodies
MYPT1 (Phospho Thr853) Rabbit pAb
YP0662
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ELISA Kits
Total MYPT1 Cell-Based Colorimetric ELISA Kit
KA4192C
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ELISA Kits
MYPT1 (Phospho Thr853) Cell-Based Colorimetric ELISA Kit
KA1305C
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Antigen&Target Information
Gene Name:
PPP1R12A
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Other Name:
Protein phosphatase 1 regulatory subunit 12A ;
Myosin phosphatase-targeting subunit 1 ;
Myosin phosphatase target subunit 1 ;
Protein phosphatase myosin-binding subunit ;
Myosin phosphatase-targeting subunit 1 ;
Myosin phosphatase target subunit 1 ;
Protein phosphatase myosin-binding subunit ;
show all
Database Link:
Background:
function:Regulates myosin phosphatase activity. ,PTM:Phosphorylated by CIT (Rho-associated kinase) (By similarity) . Phosphorylated cooperatively by ROCK1 and CDC42BP on Thr-696. Phosphorylated on upon DNA damage , probably by ATM or ATR. ,sequence caution:Contaminating sequence. Potential poly-A sequence. ,similarity:Contains 6 ANK repeats. ,subcellular location:Along actomyosin filaments and stress fibers. ,subunit:PP1 comprises a catalytic subunit , PPP1CA , PPP1CB or PPP1CC , and one or several targeting or regulatory subunits. PPP1R12A mediates binding to myosin. Interacts with ARHA and CIT (By similarity) . Binds PPP1R12B , ROCK1 and IL16. ,
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Cellular Localization:
Cytoplasm . Cytoplasm , cytoskeleton , stress fiber . Also along actomyosin filaments. .
show all
Tissue Expression:
Signaling Pathway
Cellular Processes >> Cellular community - eukaryotes >> Focal adhesion
Cellular Processes >> Cell motility >> Regulation of actin cytoskeleton
Organismal Systems >> Immune system >> Platelet activation
Organismal Systems >> Endocrine system >> Oxytocin signaling pathway
Organismal Systems >> Circulatory system >> Vascular smooth muscle contraction
Environmental Information Processing >> Signal transduction >> cAMP signaling pathway
Environmental Information Processing >> Signal transduction >> cGMP-PKG signaling pathway
Reference Citation({{totalcount}})
Catalog: KA1305C
Size
Price
Status
Qty.
96well
$470.00
2 weeks
0
Add to cart
Collected
Collect
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