Catalog: YD2274
Size
Price
Status
Qty.
1mg
$3,870.00
3 weeks
0
100μg
$645.00
3 weeks
0
Add to cart
Collected
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Detailed Information
Recommended Dilution Ratio
Reconstitute in sterile water for a stock solution
Formulation
Supplied as solution form in PBS, pH7.5 ./ Lyophilized from PBS, pH7.5 .
Source
Baculovirus-Insect cells
Purity
>90% as determined by SDS-PAGE
Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
Antigen&Target Information
Sequence:
A DNA sequence encoding the Human CLDN1 (Met1-Val211）was fused with the C-terminal His Tag
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Other Name:
Senescence-associated epithelial membrane protein,CLD1, SEMP1
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Background:
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq, Jul 2008]
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Cellular Localization:
Cell junction, tight junction . Cell membrane ; Multi-pass membrane protein . Basolateral cell membrane . Associates with CD81 and the CLDN1-CD81 complex localizes to the basolateral cell membrane. .
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Tissue Expression:
Strongly expressed in liver and kidney. Expressed in heart, brain, spleen, lung and testis.
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: YD2274
Size
Price
Status
Qty.
1mg
$3,870.00
3 weeks
0
100μg
$645.00
3 weeks
0
Add to cart
Collected
Collect
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