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Recombinant SARS-CoV-2(Covid-19) S1 Protein

-YD2191

Catalog: YD2191
Size
Price
Status
Qty.
1mg
$1,800.00
3 weeks

0

100μg
$600.00
3 weeks

0

Add to cart

Collected

Collect

Customized Service
Main Information
Reactivity

Human virus

Applications

ELISA, ECL, Immunogold,

MW

105kD (Calculated)

130-140kD (Observed)

Detailed Information
Recommended Dilution Ratio
Testing in progress
Source
Mammalian cells
Purity
>90% as determined by SDS-PAGE
Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week . Store at -20 to -80 °C for twelve months from the date of receipt.
MW(Calculated)
105kD
MW(Observed)
130-140kD
Antigen&Target Information
Gene Name:
S
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Protein Name:
Spike glycoprotein,Spike protein S1(S1) Surface glycoprotein
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Database Link:
Organism Gene ID SwissProt
Human QHD43416.1;
Background:
Recombinant SARS-CoV-2 S1 Protein is produced by Mammalian cells expression system and the target gene encoding Met1-Tyr695 is expressed with C-Fc Tag
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Function:
Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc.. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
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Research Areas:
For research use only .Not for use in clinical diagnostic procedures.
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Catalog: YD2191
Size
Price
Status
Qty.
1mg
$1,800.00
3 weeks

0

100μg
$600.00
3 weeks

0

Add to cart

Collected

Collect

Customized Service

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