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Catalog: YD0068
Size
Price
Status
Qty.
100μg
$280.00
3 weeks

0

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Main Information
Reactivity

Human

Applications

WB, SDS-PAGE

Detailed Information
Recommended Dilution Ratio
WB 1:500-2000
Formulation
Liquid in PBS
Source
E.coli
Purity
SDS-PAGE >90%
Storage
-20°C/6 month,-80°C for long storage
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Antigen&Target Information
Sequence:
Amino acid: 218-362, with his-MBP tag.
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Gene Name:
MAP2K4
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Protein Name:
MEK4 protein
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Other Name:
Dual specificity mitogen-activated protein kinase kinase 4 ;
MAP kinase kinase 4 ;
MAPKK 4 ;
JNK-activating kinase 1 ;
MAPK/ERK kinase 4 ;
MEK 4 ;
SAPK/ERK kinase 1 ;
SEK1 ;
Stress-activated protein kinase kinase 1 ;
SAPK kinase 1 ;
SAPKK-1 ;
SAPKK1 ;
c-Jun N-terminal kinase kinase 1 ;
JNKK ;
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Database Link:
Organism Gene ID SwissProt
Human 6416; P45985;
Mouse P47809;
Background:
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Dual specificity kinase that activates the JUN kinases MAPK8 (JNK1) and MAPK9 (JNK2) as well as MAPK14 (p38) but not MAPK1 (ERK2) or MAPK3 (ERK1).,PTM:Activated by phosphorylation on Ser/Thr by MAP kinase kinase kinases.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with SPAG9.,tissue specificity:Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.,
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Function:
MAPKKK cascade, protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process,intracellular signaling cascade, protein kinase cascade, JNK cascade, phosphorylation, stress-activated protein kinase signaling pathway, cellular response to stress,
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Cellular Localization:
Cytoplasm . Nucleus .
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Tissue Expression:
Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.
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Catalog: YD0068
Size
Price
Status
Qty.
100μg
$280.00
3 weeks

0

Add to cart

Collected

Collect

Customized Service

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