Contact Us

408-747-0189
1-877-594-3616

Quick order
Catalog: YD0058
Size
Price
Status
Qty.
100μg
$280.00
3 weeks

0

Add to cart

Collected

Collect

Customized Service
Main Information
Reactivity

Human

Applications

WB, SDS-PAGE

Detailed Information
Recommended Dilution Ratio
WB 1:500-2000
Formulation
Liquid in PBS
Source
E.coli
Purity
SDS-PAGE >90%
Storage
-20°C/6 month,-80°C for long storage
Related Products
Secondary Antibodies
Goat Anti Mouse IgG(H+L) (HRP)
RS0001

More→

Secondary Antibodies
Goat Anti Rabbit IgG(H+L) (HRP)
RS0002

More→

Primary Antibodies
β-actin (PTR2364) Mouse mAb
YM3028

More→

Primary Antibodies
GAPDH (PTR2304) Mouse mAb
YM3029

More→

Antigen&Target Information
Sequence:
Amino acid: 1-72, with his-MBP tag.
show all
Gene Name:
MAPK8 JNK1 PRKM8 SAPK1 SAPK1C
show all
Protein Name:
JNK1 protein
show all
Other Name:
Mitogen-activated protein kinase 8 ;
MAP kinase 8 ;
MAPK 8 ;
JNK-46 ;
Stress-activated protein kinase 1c ;
SAPK1c ;
Stress-activated protein kinase JNK1 ;
c-Jun N-terminal kinase 1 ;
show all
Database Link:
Organism Gene ID SwissProt
Human 5599; P45983;
Mouse Q91Y86;
Function:
MAPKKK cascade, skeletal system development, ossification, protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, apoptosis, induction of apoptosis, cell motion, intracellular signaling cascade, protein kinase cascade, JNK cascade, JUN phosphorylation, cell death, induction of apoptosis by extracellular signals, activation of pro-apoptotic gene products, response to radiation, response to UV, response to light stimulus,response to abiotic stimulus, response to inorganic substance, response to metal ion, regulation of cell death, positive regulation of cell death, programmed cell death, induction of programmed cell death, death, phosphorylation, peptidyl-threonine phosphorylation, peptidyl-threonine modification, stress-activated protein kinase signaling pathway,induction of programmed cell death in response to chemical stimulus, induction of apoptosis in response to chemical stimulus, cellular response to stress, regulation of apoptosis, positive regulation of apoptosis, negative regulation of apoptosis, regulation of programmed cell death, positive regulation of programmed cell death, negative regulation of programmed cell death, response to cadmium ion, bone development, negative regulation of cell death,
show all
Cellular Localization:
Cytoplasm . Nucleus . Cell junction, synapse . In the cortical neurons, predominantly cytoplasmic and associated with the Golgi apparatus and endosomal fraction. Increased neuronal activity increases phosphorylated form at synapses (By similarity). Colocalizes with POU5F1 in the nucleus. .
show all
Signaling Pathway
Cellular Processes >> Transport and catabolism >> Autophagy - animal Cellular Processes >> Transport and catabolism >> Mitophagy - animal Cellular Processes >> Cell growth and death >> Apoptosis Cellular Processes >> Cell growth and death >> Apoptosis - multiple species Cellular Processes >> Cell growth and death >> Necroptosis Cellular Processes >> Cellular community - eukaryotes >> Focal adhesion Cellular Processes >> Cellular community - eukaryotes >> Tight junction Organismal Systems >> Immune system >> Toll-like receptor signaling pathway Organismal Systems >> Immune system >> NOD-like receptor signaling pathway Organismal Systems >> Immune system >> RIG-I-like receptor signaling pathway Organismal Systems >> Immune system >> T cell receptor signaling pathway Organismal Systems >> Immune system >> Th1 and Th2 cell differentiation Organismal Systems >> Immune system >> Th17 cell differentiation Organismal Systems >> Immune system >> IL-17 signaling pathway Organismal Systems >> Immune system >> Fc epsilon RI signaling pathway Organismal Systems >> Endocrine system >> Insulin signaling pathway Organismal Systems >> Endocrine system >> Adipocytokine signaling pathway Organismal Systems >> Endocrine system >> GnRH signaling pathway Organismal Systems >> Endocrine system >> Prolactin signaling pathway Organismal Systems >> Endocrine system >> Relaxin signaling pathway Organismal Systems >> Endocrine system >> Growth hormone synthesis, secretion and action Organismal Systems >> Nervous system >> Dopaminergic synapse Organismal Systems >> Nervous system >> Neurotrophin signaling pathway Organismal Systems >> Sensory system >> Inflammatory mediator regulation of TRP channels Organismal Systems >> Development and regeneration >> Osteoclast differentiation Human Diseases >> Cancer: overview >> Pathways in cancer Human Diseases >> Cancer: specific types >> Colorectal cancer Human Diseases >> Cancer: specific types >> Pancreatic cancer Human Diseases >> Neurodegenerative disease >> Alzheimer disease Human Diseases >> Neurodegenerative disease >> Parkinson disease Human Diseases >> Neurodegenerative disease >> Huntington disease Human Diseases >> Neurodegenerative disease >> Spinocerebellar ataxia Human Diseases >> Neurodegenerative disease >> Prion disease Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases Environmental Information Processing >> Signal transduction >> MAPK signaling pathway Environmental Information Processing >> Signal transduction >> ErbB signaling pathway Environmental Information Processing >> Signal transduction >> Ras signaling pathway Environmental Information Processing >> Signal transduction >> Wnt signaling pathway Environmental Information Processing >> Signal transduction >> TNF signaling pathway Environmental Information Processing >> Signal transduction >> FoxO signaling pathway Environmental Information Processing >> Signal transduction >> Sphingolipid signaling pathway Environmental Information Processing >> Signal transduction >> cAMP signaling pathway
Catalog: YD0058
Size
Price
Status
Qty.
100μg
$280.00
3 weeks

0

Add to cart

Collected

Collect

Customized Service

Toggle night Mode

{{pinfoXq.title || ''}}

Catalog: {{pinfoXq.catalog || ''}}
Filter:

All

{{item.name}}

{{pinfo.title}}
-{{pinfo.catalog}}

Filter:

{{item.descr}}

Main Information
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
Learn more
Product {{index}}/{{pcount}}
Prev
Next

{{pvTitle}}

Scroll wheel zooms the picture
{{pvDescr}}