C5AR1

C5a anaphylatoxin chemotactic receptor ;
C5a-R ;
C5aR ;
CD antigen CD88 ;

function:Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis , granule enzyme release and superoxide anion production. ,PTM:Sulfation plays a critical role in the association of the receptor with C5a , but no significant role in the ability of the receptor to transduce a signal and mobilize calcium in response to a small peptide agonist. ,similarity:Belongs to the G-protein coupled receptor 1 family. ,

MAPKKK cascade , activation of MAPK activity , protein amino acid phosphorylation , phosphorus metabolic process ,phosphate metabolic process , cellular ion homeostasis , cellular calcium ion homeostasis , cellular metal ion homeostasis , chemotaxis , defense response , immune response , cellular defense response , cell surface receptor linked signal transduction , G-protein coupled receptor protein signaling pathway , activation of phospholipase C activity ,elevation of cytosolic calcium ion concentration , intracellular signaling cascade , protein kinase cascade , sensory perception , sensory perception of chemical stimulus , behavior , locomotory behavior , regulation of phospholipase activity , positive regulation of phospholipase activity , positive regulation of phospholipase C activity , phosphorylation ,regulation of phosphate metabolic process , cellular homeostasis , cellular cation homeostasis , cellular di- , tri-valent inorganic cation homeostasis , positive regulation of kinase activity , regulation of phosphorylation , taxis , homeostatic process , positive regulation of catalytic activity , regulation of MAP kinase activity , positive regulation of MAP kinase activity , regulation of kinase activity , positive regulation of molecular function , regulation of protein kinase activity ,positive regulation of protein kinase activity , chemical homeostasis , ion homeostasis , neurological system process ,cognition , regulation of phosphorus metabolic process , regulation of hydrolase activity , regulation of transferase activity , positive regulation of hydrolase activity , positive regulation of transferase activity , cytosolic calcium ion homeostasis , metal ion homeostasis , di- , tri-valent inorganic cation homeostasis , calcium ion homeostasis , cation homeostasis , cellular chemical homeostasis , regulation of lipase activity , positive regulation of lipase activity ,

Cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle . Phosphorylated C5aR colocalizes with ARRB1 and ARRB2 in cytoplasmic vesicles. .