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Total KPBB Cell-Based Colorimetric ELISA Kit

-KA4376C

Catalog: KA4376C
Size
Price
Status
Qty.
96well
$330.00
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Main Information
Reactivity

Human, Mouse

Applications

ELISA

Conjugate/Modification


Unmodified

Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
KPBB
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Other Name:
Phosphorylase b kinase regulatory subunit beta ;
Phosphorylase kinase subunit beta ;
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Database Link:
Organism Gene ID SwissProt
Human 5257; Q93100;
Mouse Q7TSH2;
Background:
disease:Defects in PHKB are the cause of glycogen storage disease type 9B (GSD9B) [MIM:261750]; also known as phosphorylase kinase deficiency of liver and muscle (PKD). GSD9B is a metabolic disorder characterized by hepathomegaly, only slightly elevated transaminases and plasma lipids, clinical improvement with increasing age, and remarkably no clinical muscle involvement. Biochemical observations suggest that this mild phenotype is caused by an incomplete holoenzyme that lacks the beta subunit, but that may possess residual activity.,enzyme regulation:By phosphorylation of various serine residues.,function:Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation.,pathway:Glycan biosynthesis; glycogen metabolism.,similarity:Belongs to the phosphorylase b kinase regulatory chain family.,subunit:Polymer of 16 chains, four each of alpha, beta, gamma, and delta. Alpha and beta are regulatory chains, gamma is the catalytic chain, and delta is calmodulin.,
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Function:
polysaccharide metabolic process, glycogen metabolic process, monosaccharide metabolic process, glucose metabolic process, cellular glucan metabolic process, generation of precursor metabolites and energy, energy reserve metabolic process, energy derivation by oxidation of organic compounds, hexose metabolic process, glucan metabolic process,cellular polysaccharide metabolic process,
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Cellular Localization:
Cell membrane ; Lipid-anchor ; Cytoplasmic side .
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Catalog: KA4376C
Size
Price
Status
Qty.
96well
$330.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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