TNFC

Lymphotoxin-beta ;
LT-beta ;
Tumor necrosis factor C ;
TNF-C ;
Tumor necrosis factor ligand superfamily member 3 ;

function:Cytokine that binds to LTBR/TNFRSF3. May play a specific role in immune response regulation. Provides the membrane anchor for the attachment of the heterotrimeric complex to the cell surface. Isoform 2 is probably non-functional.,similarity:Belongs to the tumor necrosis factor family.,subunit:Heterotrimer of either two LTB and one LTA subunits or (less prevalent) one LTB and two LTA subunits.,tissue specificity:Spleen and thymus.,

cell activation, regulation of cytokine production, regulation of L-glutamate transport, negative regulation of L-glutamate transport, immune system development, apoptosis, induction of apoptosis, immune response, regulation of mitosis, intracellular signaling cascade, cell-cell signaling, regulation of mitotic cell cycle, ectoderm development, cell death, negative regulation of cell proliferation, epidermis development, response to mechanical stimulus, response to abiotic stimulus, positive regulation of biosynthetic process, positive regulation of signal transduction, positive regulation of macromolecule biosynthetic process, regulation of cell cycle process, positive regulation of macromolecule metabolic process, regulation of protein kinase cascade, positive regulation of organelle organization, positive regulation of cell communication, positive regulation of protein kinase cascade, regulation of glucose transport,negative regulation of glucose transport, regulation of cell death, positive regulation of cell death, programmed cell death, induction of programmed cell death, death, calcium-mediated signaling, second-messenger-mediated signaling,positive regulation of cellular biosynthetic process, regulation of neurological system process, positive regulation of neurological system process, regulation of interleukin-12 production, regulation of protein localization, regulation of organic acid transport, negative regulation of organic acid transport, regulation of organelle organization, regulation of cytokine biosynthetic process, positive regulation of cytokine biosynthetic process, regulation of cell proliferation,regulation of apoptosis, positive regulation of apoptosis, regulation of programmed cell death, positive regulation of programmed cell death, regulation of I-kappaB kinase/NF-kappaB cascade, positive regulation of I-kappaB kinase/NF-kappaB cascade, regulation of ion transport, negative regulation of ion transport, regulation of neuron apoptosis,positive regulation of neuron apoptosis, skin development, regulation of system process, regulation of anion transport, regulation of interleukin-12 biosynthetic process, positive regulation of interleukin-12 biosynthetic process,positive regulation of cell cycle, positive regulation of mitosis, regulation of glucose import, negative regulation of glucose import, hemopoietic or lymphoid organ development, lymph node development, regulation of synaptic transmission, positive regulation of synaptic transmission, positive regulation of transport, negative regulation of transport, positive regulation of cellular component organization, positive regulation of protein transport, regulation of protein transport, positive regulation of multicellular organismal process, regulation of cell cycle, regulation of nuclear division, positive regulation of nuclear division, regulation of amine transport, negative regulation of amine transport,regulation of amino acid transport, negative regulation of amino acid transport, regulation of transmission of nerve impulse, positive regulation of transmission of nerve impulse, regulation of establishment of protein localization,

Membrane ; Single-pass type II membrane protein .

Spleen and thymus.