Catalog: KA4327C
Size
Price
Status
Qty.
96well
$330.00
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0
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Main Information
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
Unmodified
Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
Related Products
Primary Antibodies
XRCC1 Rabbit pAb
YT4917
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Primary Antibodies
XRCC1 Mouse mAb
YM1417
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ELISA Kits
Total XRCC1 Cell-Based Colorimetric ELISA Kit
KA4327C
More→
ELISA Kits
Human TNF-α(Tumor Necrosis Factor Alpha) ELISA Kit
KE1372
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ELISA Kits
Human RNASE3/ECP(Ribonuclease A3/Eosinophil Cationic Protein) ELISA Kit
KE1709
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Antigen&Target Information
Gene Name:
XRCC1
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Other Name:
DNA repair protein XRCC1 ;
X-ray repair cross-complementing protein 1 ;
X-ray repair cross-complementing protein 1 ;
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Background:
function:Corrects defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents.,polymorphism:Carriers of the polymorphic Gln-399 allele may be at greater risk for tobacco- and age-related DNA damage.,PTM:Phosphorylation of Ser-371 causes dimer dissociation. Phosphorylation by CK2 promotes interaction with APTX and APLF.,PTM:Sumoylated.,similarity:Contains 2 BRCT domains.,subcellular location:Accumulates at sites of DNA damage.,subunit:Homodimer. Interacts with polynucleotide kinase (PNK), DNA polymerase-beta (POLB) and DNA ligase III (LIG3). Interacts with APTX and APLF.,
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Function:
single strand break repair, response to hypoxia, DNA metabolic process, DNA repair, response to DNA damage stimulus, response to organic substance, cellular response to stress, response to drug, response to oxygen levels,
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Cellular Localization:
Nucleus . Moves from the nucleoli to the global nuclear chromatin upon DNA damage. .
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Tissue Expression:
Expressed in fibroblasts, retinal pigmented epithelial cells and lymphoblastoid cells (at protein level).
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Reference Citation({{totalcount}})
Catalog: KA4327C
Size
Price
Status
Qty.
96well
$330.00
In stock
0
Add to cart
Collected
Collect
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