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Total SSB Cell-Based Colorimetric ELISA Kit

-KA4290C

Catalog: KA4290C
Size
Price
Status
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96well
$330.00
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Main Information
Reactivity

Human

Applications

ELISA

Conjugate/Modification


Unmodified

Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
SSB
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Other Name:
Lupus La protein ;
La autoantigen ;
La ribonucleoprotein ;
Sjoegren syndrome type B antigen ;
SS-B ;
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Database Link:
Organism Gene ID SwissProt
Human 6741; P05455;
Mouse P32067;
Background:
disease:Sera from patients with systemic lupus erythematosus (SLE) often contain antibodies that react with the normal cellular La protein as if this antigen was foreign.,function:La protein plays a role in the transcription of RNA polymerase III. It is most probably a transcription termination factor. Binds to the 3' termini of virtually all nascent polymerase III transcripts. It is associated with precursor forms of RNA polymerase III transcripts including tRNA and 4.5S, 5S, 7S, and 7-2 RNAs.,PTM:Phosphorylated. The phosphorylation sites are at the C-terminal part of the protein.,PTM:The N-terminus is blocked.,similarity:Contains 1 HTH La-type RNA-binding domain.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Interacts with DDX15. May interact with RUFY1.,
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Function:
RNA processing, tRNA metabolic process, tRNA modification, tRNA processing, histone mRNA metabolic process, RNA modification, mRNA metabolic process, ncRNA processing, ncRNA metabolic process,
show all
Cellular Localization:
Nucleus .
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Catalog: KA4290C
Size
Price
Status
Qty.
96well
$330.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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