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Main Information
Reactivity
Human, Mouse, Rat
Applications
ELISA
Conjugate/Modification
Unmodified
Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
PLCB3
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Other Name:
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 ;
Phosphoinositide phospholipase C-beta-3 ;
Phospholipase C-beta-3 ;
PLC-beta-3 ;
Phosphoinositide phospholipase C-beta-3 ;
Phospholipase C-beta-3 ;
PLC-beta-3 ;
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Background:
catalytic activity:1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.,cofactor:Calcium.,function:The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.,similarity:Contains 1 C2 domain.,similarity:Contains 1 PI-PLC X-box domain.,similarity:Contains 1 PI-PLC Y-box domain.,subunit:Interacts with SHANK2 (By similarity). Interacts with LPAR2.,
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Function:
phospholipid metabolic process, intracellular signaling cascade, phospholipid catabolic process, lipid catabolic process,organophosphate metabolic process, cellular lipid catabolic process,
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Cellular Localization:
Cytoplasm . Membrane . Nucleus . And particulate fractions. .
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Signaling Pathway
Cellular Processes >> Cellular community - eukaryotes >> Gap junction Organismal Systems >> Immune system >> Platelet activation Organismal Systems >> Immune system >> Neutrophil extracellular trap formation Organismal Systems >> Immune system >> NOD-like receptor signaling pathway Organismal Systems >> Immune system >> Chemokine signaling pathway Organismal Systems >> Endocrine system >> Insulin secretion Organismal Systems >> Endocrine system >> Glucagon signaling pathway Organismal Systems >> Endocrine system >> GnRH signaling pathway Organismal Systems >> Endocrine system >> Estrogen signaling pathway Organismal Systems >> Endocrine system >> Oxytocin signaling pathway Organismal Systems >> Endocrine system >> Relaxin signaling pathway Organismal Systems >> Endocrine system >> Growth hormone synthesis, secretion and action Organismal Systems >> Endocrine system >> Thyroid hormone signaling pathway Organismal Systems >> Endocrine system >> Aldosterone synthesis and secretion Organismal Systems >> Circulatory system >> Adrenergic signaling in cardiomyocytes Organismal Systems >> Circulatory system >> Vascular smooth muscle contraction Organismal Systems >> Nervous system >> Glutamatergic synapse Organismal Systems >> Nervous system >> Cholinergic synapse Organismal Systems >> Nervous system >> Dopaminergic synapse Organismal Systems >> Sensory system >> Inflammatory mediator regulation of TRP channels Human Diseases >> Cancer: overview >> Pathways in cancer Human Diseases >> Neurodegenerative disease >> Alzheimer disease Human Diseases >> Neurodegenerative disease >> Huntington disease Human Diseases >> Neurodegenerative disease >> Spinocerebellar ataxia Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases Environmental Information Processing >> Signal transduction >> Rap1 signaling pathway Environmental Information Processing >> Signal transduction >> Wnt signaling pathway Environmental Information Processing >> Signal transduction >> Apelin signaling pathway Environmental Information Processing >> Signal transduction >> Calcium signaling pathway Environmental Information Processing >> Signal transduction >> Phospholipase D signaling pathway Environmental Information Processing >> Signal transduction >> Sphingolipid signaling pathway Environmental Information Processing >> Signal transduction >> cGMP-PKG signaling pathway
Catalog: KA4247C
Size
Price
Status
Qty.
96well
$330.00
In stock
0
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