Contact Us

408-747-0189
1-877-594-3616

Quick order

Total MNK1 Cell-Based Colorimetric ELISA Kit

-KA4184C

Main Information
Reactivity

Human, Mouse

Applications

ELISA

Conjugate/Modification


Unmodified

Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
Related Products
Primary Antibodies
MNK1 Rabbit pAb
YT2805

More→

Primary Antibodies
MNK1 (Phospho Thr250) Rabbit pAb
YP1051

More→

Primary Antibodies
MNK1 (Phospho Thr385) Rabbit pAb
YP0824

More→

Primary Antibodies
MNK1 (Phospho Thr255) Rabbit pAb
YP0427

More→

ELISA Kits
Total MNK1 Cell-Based Colorimetric ELISA Kit
KA4184C

More→

ELISA Kits
MNK1 (Phospho Thr385) Cell-Based Colorimetric ELISA Kit
KA1755C

More→

ELISA Kits
MNK1 (Phospho Thr255) Cell-Based Colorimetric ELISA Kit
KA1710C

More→

Antigen&Target Information
Gene Name:
MKNK1
show all
Other Name:
MAP kinase-interacting serine/threonine-protein kinase 1 ;
MAP kinase signal-integrating kinase 1 ;
MAPK signal-integrating kinase 1 ;
Mnk1 ;
show all
Database Link:
Organism Gene ID SwissProt
Human 8569; Q9BUB5;
Mouse 17346; O08605;
Background:
MAP kinase interacting serine/threonine kinase 1(MKNK1) Homo sapiens This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2012],
show all
Function:
Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Phosphorylated and activated by the p38 kinases and kinases in the Erk pathway.,Function:May play a role in the response to environmental stress and cytokines. Appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.,PTM:Dual phosphorylation of Thr-250 and Thr-255 activates the kinase. Phosphorylation of Thr-385 activates the kinase.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with the C-terminal regions of EIF4G1 and EIF4G2. Also binds to dephosphorylated ERK1 and ERK2, and to the p38 kinases.,tissue specificity:Ubiquitous.,
show all
Cellular Localization:
[Isoform 2]: Cytoplasm.; [Isoform 3]: Cytoplasm. Nucleus.
show all
Tissue Expression:
Ubiquitous.
show all
Catalog: KA4184C
Size
Price
Status
Qty.
96well
$330.00
In stock

0

Add to cart

Collect

Customized Service

Recently Viewed Products

Clear all

    Toggle night Mode

    Catalog:
    Filter:

    All

    -

    Filter:

    Main Information
    Conjugate/Modification
    /
    Learn more
    Product /0
    Prev
    Next

    Scroll wheel zooms the picture