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Total IL-3Rβ Cell-Based Colorimetric ELISA Kit

-KA4136C

Catalog: KA4136C
Size
Price
Status
Qty.
96well
$330.00
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Main Information
Reactivity

Human, Mouse, Rat

Applications

ELISA

Conjugate/Modification


Unmodified

Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
CSF2RB
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Other Name:
Cytokine receptor common subunit beta ;
CDw131 ;
GM-CSF/IL-3/IL-5 receptor common beta subunit ;
CD antigen CD131 ;
show all
Database Link:
Organism Gene ID SwissProt
Human 1439; P32927;
Mouse P26955;
Background:
disease:Defects in CSF2RB are a cause of congenital pulmonary alveolar proteinosis (PAP) [MIM:265120]. PAP is an autosomal recessive fatal respiratory disease.,domain:The box 1 motif is required for JAK interaction and/or activation.,domain:The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.,function:High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor.,similarity:Belongs to the type I cytokine receptor family. Type 4 subfamily.,similarity:Contains 2 fibronectin type-III domains.,subunit:Heterodimer of an alpha and a beta subunit. The beta subunit is common to the IL3, IL5 and GM-CSF receptors.,
show all
Function:
respiratory gaseous exchange, cytokine-mediated signaling pathway,
show all
Cellular Localization:
Membrane; Single-pass type I membrane protein.
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Catalog: KA4136C
Size
Price
Status
Qty.
96well
$330.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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