KCNJ3

G protein-activated inward rectifier potassium channel 1 ;
GIRK-1 ;
Inward rectifier K ;
+ ;
channel Kir3.1 ;
Potassium channel, inwardly rectifying subfamily J member 3 ;

function:This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.,similarity:Belongs to the inward rectifier-type potassium channel family.,subunit:Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.,

ion transport, cation transport, potassium ion transport, monovalent inorganic cation transport, metal ion transport,

Membrane; Multi-pass membrane protein.