Catalog: KA4096C
Size
Price
Status
Qty.
96well
$330.00
In stock
0
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Main Information
Reactivity
Human, Mouse
Applications
ELISA
Conjugate/Modification
Unmodified
Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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Total FER Cell-Based Colorimetric ELISA Kit
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Antigen&Target Information
Gene Name:
FER
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Other Name:
Tyrosine-protein kinase Fer ;
Feline encephalitis virus-related kinase FER ;
Fujinami poultry sarcoma/Feline sarcoma-related protein Fer ;
Proto-oncogene c-Fer ;
Tyrosine kinase 3 ;
p94-Fer ;
Feline encephalitis virus-related kinase FER ;
Fujinami poultry sarcoma/Feline sarcoma-related protein Fer ;
Proto-oncogene c-Fer ;
Tyrosine kinase 3 ;
p94-Fer ;
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Background:
catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Tyrosine kinase of the non-receptor type. Probably performs an important function, perhaps in regulatory processes such as cell cycle control.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.,similarity:Contains 1 FCH domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,subcellular location:Associated with the chromatin.,tissue specificity:Expressed in a variety of lymphoid cell lines.,
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Function:
protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, chemotaxis, cell adhesion, intracellular signaling cascade, behavior, locomotory behavior, phosphorylation, peptidyl-tyrosine phosphorylation, peptidyl-tyrosine modification, biological adhesion, taxis, protein amino acid autophosphorylation,
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Cellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection. Cell junction. Membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus. Cytoplasm, cell cortex. Associated with the chromatin. Detected on microtubules in polarized and motile vascular endothelial cells. Colocalizes with F-actin at the cell cortex. Colocalizes with PECAM1 and CTNND1 at nascent cell-cell contacts.
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Tissue Expression:
Isoform 1 is detected in normal colon and in fibroblasts (at protein level). Isoform 3 is detected in normal testis, in colon carcinoma-derived metastases in lung, liver and ovary, and in colon carcinoma and hepato carcinoma cell lines (at protein level). Isoform 3 is not detected in normal colon or in normal fibroblasts (at protein level). Widely expressed.
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Reference Citation({{totalcount}})
Catalog: KA4096C
Size
Price
Status
Qty.
96well
$330.00
In stock
0
Add to cart
Collected
Collect
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