CDC6

Cell division control protein 6 homolog ;
CDC6-related protein ;
Cdc18-related protein ;
HsCdc18 ;
p62 ;
cdc6 ;
HsCDC6 ;

function:Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.,similarity:Belongs to the CDC6/cdc18 family.,subcellular location:The protein is nuclear in G1 and cytoplasmic in S-phase cells.,subunit:Interacts with PCNA, ORC1L, cyclin-CDK and HUWE1.,

cell cycle checkpoint, DNA replication checkpoint, regulation of cyclin-dependent protein kinase activity, G1 phase of mitotic cell cycle, M phase of mitotic cell cycle, mitotic cell cycle, M phase, nuclear division, DNA metabolic process, DNA replication, regulation of DNA replication, cell cycle, mitosis, traversing start control point of mitotic cell cycle, regulation of mitotic cell cycle, negative regulation of DNA replication, negative regulation of cell proliferation, negative regulation of biosynthetic process, negative regulation of macromolecule biosynthetic process, negative regulation of macromolecule metabolic process, regulation of phosphate metabolic process, cell cycle process, cell cycle phase,regulation of DNA replication initiation, negative regulation of cellular biosynthetic process, DNA integrity checkpoint,negative regulation of DNA replication initiation, regulation of cell proliferation, regulation of phosphorylation,regulation of kinase activity, regulation of protein kinase activity, negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process, organelle fission, regulation of DNA metabolic process, negative regulation of DNA metabolic process, negative regulation of nitrogen compound metabolic process, regulation of phosphorus metabolic process, cell division, G1 phase, interphase, interphase of mitotic cell cycle, regulation of transferase activity, regulation of cell cycle,

Nucleus . Cytoplasm . The protein is nuclear in G1 and cytoplasmic in S-phase cells (PubMed:9566895). .