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Total CaMK2-β/γ/δ Cell-Based Colorimetric ELISA Kit

-KA4023C

Catalog: KA4023C
Size
Price
Status
Qty.
96well
$330.00
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Main Information
Reactivity

Human, Mouse, Rat

Applications

ELISA

Conjugate/Modification


Unmodified

Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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Total CaMK2-β/γ/δ Cell-Based Colorimetric ELISA Kit
KA4023C

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Antigen&Target Information
Gene Name:
CAMK2B
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Database Link:
Organism Gene ID SwissProt
Human 816;817;818; Q13554;Q13555;Q13557;
Background:
alternative products:The variable region of the CAMK2B protein is encoded by at least 7 exons (V1 to V7). Alternative splicing within this region gives rise to CAMK2B isoforms,catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Autophosphorylation of CAMK2 plays an important role in the regulation of the kinase activity.,function:CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses, it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.,similarity:Contains 1 protein kinase domain.,subunit:CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Interacts with SYNGAP1 and CAMK2N2 (By similarity). Interacts with MPDZ.,tissue specificity:Widely expressed. Expressed in adult and fetal brain. Expression is slightly lower in fetal brain.,
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Function:
G1/S transition of mitotic cell cycle, mitotic cell cycle, protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, ion transport, cation transport, calcium ion transport, cell cycle, di-, tri-valent inorganic cation transport, phosphorylation, cell cycle process, cell cycle phase, metal ion transport, protein amino acid autophosphorylation, interphase, interphase of mitotic cell cycle,
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Cellular Localization:
Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Sarcoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell junction, synapse . In slow-twitch muscle, evenly distributed between longitudinal SR and junctional SR.
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Tissue Expression:
Widely expressed. Expressed in adult and fetal brain. Expression is slightly lower in fetal brain. Expressed in skeletal muscle.
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Catalog: KA4023C
Size
Price
Status
Qty.
96well
$330.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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