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Total AurB/C Cell-Based Colorimetric ELISA Kit

-KA4007C

Catalog: KA4007C
Size
Price
Status
Qty.
96well
$330.00
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Main Information
Reactivity

Human, Mouse, Rat

Applications

ELISA

Conjugate/Modification


Unmodified

Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
AURKB/AURKC
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Database Link:
Organism Gene ID SwissProt
Human 9212;6795; Q96GD4;Q9UQB9;
Function:
M phase of mitotic cell cycle, mitotic cell cycle, M phase, nuclear division, cytokinesis, protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, cell cycle, mitosis, protein localization,phosphorylation, cell cycle process, cell cycle phase, protein localization to kinetochore, cellular protein localization,organelle fission, cell division, cellular macromolecule localization,
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Cellular Localization:
Nucleus . Chromosome . Chromosome, centromere . Chromosome, centromere, kinetochore . Cytoplasm, cytoskeleton, spindle . Midbody . Localizes on chromosome arms and inner centromeres from prophase through metaphase and then transferring to the spindle midzone and midbody from anaphase through cytokinesis (PubMed:20929775). Colocalized with gamma tubulin in the midbody (PubMed:17726514). Proper localization of the active, Thr-232-phosphorylated form during metaphase may be dependent upon interaction with SPDYC (PubMed:20605920). Colocalized with SIRT2 during cytokinesis with the midbody (PubMed:17726514). Localization (and probably targeting of the CPC) to the inner centromere occurs predominantly in regions with overlapping mitosis-specific histone phosphorylations H3pT3 and H2ApT12 (PubMed:20929775). .
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Tissue Expression:
High level expression seen in the thymus. It is also expressed in the spleen, lung, testis, colon, placenta and fetal liver. Expressed during S and G2/M phase and expression is up-regulated in cancer cells during M phase. ; [Isoform 3]: Not expressed in normal liver, high expression in metastatic liver.
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Catalog: KA4007C
Size
Price
Status
Qty.
96well
$330.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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