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Cleaved MMP-15 (Tyr132) Cell-Based Colorimetric ELISA Kit

-KA3968C

Catalog: KA3968C
Size
Price
Status
Qty.
96well
$330.00
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Main Information
Reactivity

Human

Applications

ELISA

Conjugate/Modification


Unmodified

Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
MMP15
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Other Name:
Matrix metalloproteinase-15 ;
MMP-15 ;
Membrane-type matrix metalloproteinase 2 ;
MT-MMP 2 ;
MTMMP2 ;
Membrane-type-2 matrix metalloproteinase ;
MT2-MMP ;
MT2MMP ;
SMCP-2 ;
show all
Database Link:
Organism Gene ID SwissProt
Human 4324; P51511;
Mouse O54732;
Background:
cofactor:Binds 1 zinc ion per subunit.,cofactor:Calcium.,domain:The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.,function:Endopeptidase that degrades various components of the extracellular matrix. May activate progelatinase A.,PTM:The precursor is cleaved by a furin endopeptidase.,similarity:Belongs to the peptidase M10A family.,similarity:Contains 4 hemopexin-like domains.,tissue specificity:Appeared to be synthesized preferentially in liver, placenta, testis, colon and intestine. Substantial amounts are also detected in pancreas, kidney, lung, heart and skeletal muscle.,
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Function:
proteolysis,
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Cellular Localization:
Membrane ; Single-pass type I membrane protein ; Extracellular side .
show all
Tissue Expression:
Appeared to be synthesized preferentially in liver, placenta, testis, colon and intestine. Substantial amounts are also detected in pancreas, kidney, lung, heart and skeletal muscle.
show all
Catalog: KA3968C
Size
Price
Status
Qty.
96well
$330.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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