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Cleaved ITI-H1 (Asp672) Cell-Based Colorimetric ELISA Kit

-KA3963C

Catalog: KA3963C
Size
Price
Status
Qty.
96well
$330.00
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Main Information
Reactivity

Human, Mouse

Applications

ELISA

Conjugate/Modification


Unmodified

Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
ITIH1
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Other Name:
Inter-alpha-trypsin inhibitor heavy chain H1 ;
ITI heavy chain H1 ;
ITI-HC1 ;
Inter-alpha-inhibitor heavy chain 1 ;
Inter-alpha-trypsin inhibitor complex component III ;
Serum-derived hyaluronan-associated protein ;
SHAP ;
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Database Link:
Organism Gene ID SwissProt
Human 3697; P19827;
Mouse Q61702;
Background:
function:Contains a potential peptide which could stimulate a broad spectrum of phagocytotic cells.,function:May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.,mass spectrometry: PubMed:9677337,polymorphism:There are 3 common alleles; ITIH1*1 with Glu-585/Gln-595, ITIH1*2 with Val-585/Arg-595 and ITIH1*3 with Glu-585/Arg-595.,PTM:Heavy chains are linked to bikunin via chondroitin 4-sulfate esterified to the alpha-carboxyl of the C-terminal aspartate after propeptide cleavage.,PTM:The S-linked glycan is composed of two units of either Glc or Gal.,similarity:Belongs to the ITIH family.,similarity:Contains 1 VWFA domain.,subunit:I-alpha-I plasma protease inhibitors are assembled from one or two heavy chains (H1, H2 or H3) and one light chain, bikunin. Inter-alpha-inhibitor (I-alpha-I) is composed of H1, H2 and bikunin, inter-alpha-like inhibitor (I-alpha-LI) of H2 and bikunin, and pre-alpha-inhibitor (P-alpha-I) of H3 and bikunin.,
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Function:
cell activation, polysaccharide metabolic process, aminoglycan metabolic process, glycosaminoglycan metabolic process, hyaluronan metabolic process, leukocyte activation,
show all
Cellular Localization:
Secreted.
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Catalog: KA3963C
Size
Price
Status
Qty.
96well
$330.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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