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Cleaved Factor X/ Factor X LC (Ala41) Cell-Based Colorimetric ELISA Kit

-KA3946C

Catalog: KA3946C
Size
Price
Status
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96well
$330.00
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Main Information
Reactivity

Human

Applications

ELISA

Conjugate/Modification


Unmodified

Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
F10
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Other Name:
Coagulation factor X ;
Stuart factor ;
Stuart-Prower factor ;
[Cleaved into: Factor X light chain ;
Factor X heavy chain ;
Activated factor Xa heavy chain]
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Database Link:
Organism Gene ID SwissProt
Human 2159; P00742;
Mouse O88947;
Background:
catalytic activity:Selective cleavage of Arg-|-Thr and then Arg-|-Ile bonds in prothrombin to form thrombin.,function:Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.,online information:Factor X entry,PTM:N- and O-glycosylated.,PTM:The activation peptide is cleaved by factor IXa (in the intrinsic pathway), or by factor VIIa (in the extrinsic pathway).,PTM:The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.,PTM:The vitamin K-dependent, enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 Gla (gamma-carboxy-glutamate) domain.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 2 EGF-like domains.,subunit:The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds.,tissue specificity:Plasma; synthesized in the liver.,
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Function:
proteolysis, blood coagulation, blood coagulation, extrinsic pathway, hemostasis, response to wounding, positive regulation of signal transduction, regulation of protein kinase cascade, positive regulation of cell communication,positive regulation of protein kinase cascade, regulation of cell migration, positive regulation of cell migration,regulation of locomotion, positive regulation of locomotion, wound healing, coagulation, regulation of body fluid levels,regulation of cell motion, positive regulation of cell motion, regulation of protein kinase B signaling cascade, positive regulation of protein kinase B signaling cascade,
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Cellular Localization:
Secreted.
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Tissue Expression:
Plasma; synthesized in the liver.
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Catalog: KA3946C
Size
Price
Status
Qty.
96well
$330.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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