Catalog: KA3942C
Size
Price
Status
Qty.
96well
$330.00
In stock
0
Add to cart
Collected
Collect
Main Information
Reactivity
Human
Applications
ELISA
Conjugate/Modification
Unmodified
Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
Related Products
Primary Antibodies
Cathepsin L Rabbit pAb
YT5124
More→
Primary Antibodies
Cleaved Cathepsin L1 HC (Thr288) Rabbit pAb
YC0041
More→
ELISA Kits
Cleaved Cathepsin L1 HC (Thr288) Cell-Based Colorimetric ELISA Kit
KA3942C
More→
ELISA Kits
Human TNF-α(Tumor Necrosis Factor Alpha) ELISA Kit
KE1372
More→
ELISA Kits
Human RNASE3/ECP(Ribonuclease A3/Eosinophil Cationic Protein) ELISA Kit
KE1709
More→
Antigen&Target Information
Gene Name:
CTSL1
show all
Other Name:
Cathepsin L1 ;
Major excreted protein ;
MEP ;
[Cleaved into: Cathepsin L1 heavy chain ;
Cathepsin L1 light chain]
Major excreted protein ;
MEP ;
[Cleaved into: Cathepsin L1 heavy chain ;
Cathepsin L1 light chain]
show all
Background:
catalytic activity:Specificity close to that of papain. As compared to cathepsin B, cathepsin L exhibits higher activity toward protein substrates, but has little activity on Z-Arg-Arg-NHMec, and no peptidyl-dipeptidase activity.,function:Important for the overall degradation of proteins in lysosomes.,similarity:Belongs to the peptidase C1 family.,subunit:Dimer of a heavy and a light chain linked by disulfide bonds.,
show all
Function:
proteolysis,
show all
Cellular Localization:
Lysosome . Apical cell membrane ; Peripheral membrane protein ; Extracellular side . Cytoplasmic vesicle, secretory vesicle, chromaffin granule . Secreted, extracellular space . Secreted . Localizes to the apical membrane of thyroid epithelial cells. Released at extracellular space by activated dendritic cells and macrophages. .; [Isoform 2]: Nucleus . Translation initiation at downstream start sites allows the synthesis of isoforms that are devoid of a signal peptide and do not transit through the endoplasmic reticulum to localize to the nucleus (PubMed:15099520). Nuclear location varies during the cell cycle, with higher levels during S phase (PubMed:15099520). .
show all
Signaling Pathway
Cellular Processes >> Transport and catabolism >> Phagosome
Cellular Processes >> Transport and catabolism >> Lysosome
Cellular Processes >> Transport and catabolism >> Autophagy - animal
Cellular Processes >> Cell growth and death >> Apoptosis
Organismal Systems >> Immune system >> Antigen processing and presentation
Human Diseases >> Immune disease >> Rheumatoid arthritis
Reference Citation({{totalcount}})
Catalog: KA3942C
Size
Price
Status
Qty.
96well
$330.00
In stock
0
Add to cart
Collected
Collect
Recently Viewed Products
Clear allPRODUCTS
CUSTOMIZED
ABOUT US
Toggle night Mode
{{pinfoXq.title || ''}}
Catalog: {{pinfoXq.catalog || ''}}
Filter：
All
{{item.name}}
{{pinfo.title}}
-{{pinfo.catalog}}
Main Information
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
Product {{index}}/{{pcount}}
Prev
Next
{{pvTitle}}
Scroll wheel zooms the picture
{{pvDescr}}