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Cleaved Aggrecan (Asp369) Cell-Based Colorimetric ELISA Kit

-KA3916C

Catalog: KA3916C
Size
Price
Status
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96well
$330.00
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Main Information
Target

Aggrecan core protein

Reactivity

Human, Rat

Applications

ELISA

Conjugate/Modification


Unmodified

Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
ACAN AGC1 CSPG1 MSK16
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Protein Name:
Aggrecan core protein
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Other Name:
Aggrecan core protein ;
Cartilage-specific proteoglycan core protein ;
CSPCP ;
Chondroitin sulfate proteoglycan core protein 1 ;
Chondroitin sulfate proteoglycan 1 ;
[Cleaved into: Aggrecan core protein 2]
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Database Link:
Organism Gene ID SwissProt
Human 176; P16112;
Mouse 11595; Q61282;
Rat 58968; P07897;
Background:
This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene. [provided by RefSeq, Jul 2008],
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Function:
This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region.
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Cellular Localization:
Secreted, extracellular space, extracellular matrix .
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Tissue Expression:
Restricted to cartilages.
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Catalog: KA3916C
Size
Price
Status
Qty.
96well
$330.00
In stock

0

Add to cart

Collected

Collect

Customized Service

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