Contact Us

408-747-0189
1-877-594-3616

Quick order

Total Histone H4 Cell-Based Colorimetric ELISA Kit

-KA3910C

Catalog: KA3910C
Size
Price
Status
Qty.
96well
$330.00
In stock

0

Add to cart

Collected

Collect

Customized Service
Main Information
Target

Histone H4

Reactivity

Human, Mouse, Rat

Applications

ELISA

Conjugate/Modification


Unmodified

Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
Related Products
Primary Antibodies
Histone H4 Rabbit pAb
YT2174

More→

Primary Antibodies
Histone H4 (Phospho Ser47) Rabbit pAb
YP1183

More→

Primary Antibodies
Histone H4 (Mono Methyl Arg3) Mouse pAb
YM3322

More→

Primary Antibodies
Histone H4 (Mono Methyl Lys79) Mouse pAb
YM3282

More→

Primary Antibodies
Histone H4 (Acetyl Lys16) Rabbit pAb
YK0014

More→

Primary Antibodies
Histone H4 (Acetyl Lys12) Rabbit pAb
YK0013

More→

Primary Antibodies
Histone H4 (Acetyl Lys8) Rabbit pAb
YK0012

More→

Primary Antibodies
Histone H4 (Acetyl Lys5) Rabbit pAb
YK0011

More→

Primary Antibodies
Histone H4 (Mono Methyl Lys21) Rabbit pAb
YH0011

More→

ELISA Kits
Total Histone H4 Cell-Based Colorimetric ELISA Kit
KA3911C

More→

ELISA Kits
Total Histone H4 Cell-Based Colorimetric ELISA Kit
KA3910C

More→

ELISA Kits
Total Histone H4 Cell-Based Colorimetric ELISA Kit
KA3909C

More→

ELISA Kits
Total Histone H4 Cell-Based Colorimetric ELISA Kit
KA3131C

More→

ELISA Kits
Histone H4 (Phospho Ser47) Cell-Based Colorimetric ELISA Kit
KA1787C

More→

ELISA Kits
Histone H4 (Phospho Ser47) Cell-Based Colorimetric ELISA Kit
KA1103C

More→

Antigen&Target Information
Gene Name:
HIST1H4A/HIST1H4B/HIST1H4C/HIST1H4D/HIST1H4E/HIST1H4F/HIST1H4H/HIST1H4I/HIST1H4J/HIST1H4K/HIST1H4L/HIST2H4A/HIST2H4B/HIST4H4
show all
Protein Name:
Histone H4
show all
Other Name:
Histone H4
show all
Database Link:
Organism Gene ID SwissProt
Human 121504;554313;8294;8359;8360;8361;8362;8363;8364;8365;8366;8367;8368;8370; P62805;
Mouse 100041230; P62806;
Rat 100360950; P62804;
Background:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33. [provided by RefSeq, Aug 2015],
show all
Function:
Function:Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.,PTM:Acetylation at Lys-6, Lys-9, Lys-13 and Lys-17 occurs in coding regions of the genome but not in heterochromatin.,PTM:Citrullination at Arg-4 by PADI4 impairs methylation.,PTM:Monomethylated, dimethylated or trimethylated at Lys-21. Monomethylation is performed by SET8. Trimethylation is performed by SUV420H1 and SUV420H2 and induces gene silencing.,PTM:Monomethylation at Arg-4 by PRMT1 favors acetylation at Lys-9 and Lys-13. Demethylation is performed by JMJD6.,PTM:Sumoylated, which is associated with transcriptional repression.,PTM:Ubiquitinated by the CUL4-DDB-RBX1 complex in response to ultraviolet irradiation. This may weaken the interaction between histones and DNA and facilitate DNA accessibility to repair proteins.,similarity:Belongs to the histone H4 family.,subunit:The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.,
show all
Cellular Localization:
Nucleus. Chromosome.
show all
Tissue Expression:
B-cell lymphoma,Bone marrow,Brain,Clones donated by HIP,Corpus call
show all
Research Areas:
>>Neutrophil extracellular trap formation ;
>>Alcoholism ;
>>Viral carcinogenesis ;
>>Systemic lupus erythematosus
show all
Catalog: KA3910C
Size
Price
Status
Qty.
96well
$330.00
In stock

0

Add to cart

Collected

Collect

Customized Service

Toggle night Mode

{{pinfoXq.title || ''}}

Catalog: {{pinfoXq.catalog || ''}}
Filter:

All

{{item.name}}

{{pinfo.title}}
-{{pinfo.catalog}}

Filter:

{{item.descr}}

Main Information
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
Learn more
Product {{index}}/{{pcount}}
Prev
Next

{{pvTitle}}

Scroll wheel zooms the picture
{{pvDescr}}