Catalog: KE1261
Size
Price
Status
Qty.
5*96well
$1,850.00
2 weeks
0
2*96well
$740.00
2 weeks
0
96well
$370.00
2 weeks
0
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Main Information
Reactivity
Human
Applications
ELISA
Conjugate/Modification
Unmodified
Detailed Information
Specificity
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Storage
2-8°C/6 months,Ship by ice bag
Modification
Unmodified
Sample Type
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Detection Method
Colorimetric
Sensitivity
32-2000 pg/ml
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RS0002
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YM3028
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Antigen&Target Information
Specificity:
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
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Gene Name:
FIGF
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Protein Name:
Vascular endothelial growth factor D
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Other Name:
FIGF ;
VEGFD ;
Vascular endothelial growth factor D ;
VEGF-D ;
c-Fos-induced growth factor ;
FIGF
VEGFD ;
Vascular endothelial growth factor D ;
VEGF-D ;
c-Fos-induced growth factor ;
FIGF
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Background:
function:Growth factor active in angiogenesis , lymphangiogenesis and endothelial cell growth , stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in the formation of the venous and lymphatic vascular systems during embryogenesis , and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (Flk1) and VEGFR-3 (Flt4) receptors. ,PTM:Undergoes a complex proteolytic maturation which generates a variety of processed secreted forms with increased activity toward VEGFR-3 and VEGFR-2. VEGF-D first form an antiparallel homodimer linked by disulfide bonds before secretion. The fully processed VEGF-D is composed mostly of two VEGF homology domains (VHDs) bound by non-covalent interactions. ,similarity:Belongs to the PDGF/VEGF growth factor family. ,subunit:Homodimer; non-covalent and antiparallel. ,tissue specificity:Highly expressed in lung , heart , small intestine and fetal lung , and at lower levels in skeletal muscle , colon , and pancreas. ,
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Function:
angiogenesis , blood vessel development , vasculature development , cell surface receptor linked signal transduction ,enzyme linked receptor protein signaling pathway , transmembrane receptor protein tyrosine kinase signaling pathway , cell proliferation , positive regulation of cell proliferation , regulation of cell proliferation , vascular endothelial growth factor receptor signaling pathway , blood vessel morphogenesis , regulation of cell division , positive regulation of cell division ,
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Cellular Localization:
Secreted.
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Signaling Pathway
Cellular Processes >> Cellular community - eukaryotes >> Focal adhesion
Organismal Systems >> Endocrine system >> Relaxin signaling pathway
Human Diseases >> Cancer: overview >> Pathways in cancer
Environmental Information Processing >> Signal transduction >> MAPK signaling pathway
Environmental Information Processing >> Signal transduction >> Ras signaling pathway
Environmental Information Processing >> Signal transduction >> Rap1 signaling pathway
Environmental Information Processing >> Signal transduction >> TNF signaling pathway
Environmental Information Processing >> Signal transduction >> Calcium signaling pathway
Environmental Information Processing >> Signal transduction >> PI3K-Akt signaling pathway
Reference Citation({{totalcount}})
Catalog: KE1261
Size
Price
Status
Qty.
5*96well
$1,850.00
2 weeks
0
2*96well
$740.00
2 weeks
0
96well
$370.00
2 weeks
0
Add to cart
Collected
Collect
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