Catalog: KE1253
Size
Price
Status
Qty.
5*96well
$1,850.00
2 weeks
0
2*96well
$740.00
2 weeks
0
96well
$370.00
2 weeks
0
Add to cart
Collected
Collect
Main Information
Reactivity
Human
Applications
ELISA
Conjugate/Modification
Unmodified
Detailed Information
Specificity
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Storage
2-8°C/6 months,Ship by ice bag
Modification
Unmodified
Sample Type
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Detection Method
Colorimetric
Sensitivity
94-6000 pg/ml
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Antigen&Target Information
Specificity:
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
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Gene Name:
THPO
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Protein Name:
Thrombopoietin
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Other Name:
THPO ;
MGDF ;
Thrombopoietin ;
C-mpl ligand ;
ML ;
Megakaryocyte colony-stimulating factor ;
Megakaryocyte growth and development factor ;
MGDF ;
Myeloproliferative leukemia virus oncogene ligand
MGDF ;
Thrombopoietin ;
C-mpl ligand ;
ML ;
Megakaryocyte colony-stimulating factor ;
Megakaryocyte growth and development factor ;
MGDF ;
Myeloproliferative leukemia virus oncogene ligand
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Background:
disease:Defects in THPO are a cause of essential thrombocythemia (ET) [MIM:187950]. ET is inherited as an autosomal dominant trait which is characterized by elevated platelet levels due to sustained proliferation of megakaryocytes , and frequently lead to thrombotic and haemorrhagic complications. ,domain:Two-domain structure with an erythropoietin-like N-terminal and a Ser/Pro/Thr-rich C-terminal. ,function:Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets. ,similarity:Belongs to the EPO/TPO family. ,
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Function:
response to molecule of bacterial origin , immune system development , cell proliferation , positive regulation of cell proliferation , response to bacterium , response to organic substance , hemopoiesis , myeloid cell differentiation ,response to lipopolysaccharide , regulation of cell proliferation , hemopoietic or lymphoid organ development ,
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Cellular Localization:
Secreted.
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Signaling Pathway
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Catalog: KE1253
Size
Price
Status
Qty.
5*96well
$1,850.00
2 weeks
0
2*96well
$740.00
2 weeks
0
96well
$370.00
2 weeks
0
Add to cart
Collected
Collect
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