Catalog: KE1248
Size
Price
Status
Qty.
5*96well
$1,850.00
2 weeks
0
2*96well
$740.00
2 weeks
0
96well
$370.00
2 weeks
0
Add to cart
Collected
Collect
Main Information
Reactivity
Human
Applications
ELISA
Conjugate/Modification
Unmodified
Detailed Information
Specificity
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Storage
2-8°C/6 months,Ship by ice bag
Modification
Unmodified
Sample Type
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Detection Method
Colorimetric
Sensitivity
63-2000 pg/mL
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RS0002
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Antigen&Target Information
Specificity:
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
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Gene Name:
IL1RL1 DER4 ST2 T1
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Protein Name:
Interleukin-1 receptor-like 1
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Other Name:
IL1RL1 ;
DER4 ;
ST2 ;
T1 ;
Interleukin-1 receptor-like 1 ;
Protein ST2
DER4 ;
ST2 ;
T1 ;
Interleukin-1 receptor-like 1 ;
Protein ST2
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Background:
function:Receptor for interleukin-33 (IL-33) , its stimulation recruits MYD88 , IRAK1 , IRAK4 , and TRAF6 , followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2 , MAPK14 , and MAPK8. Possibly involved in helper T-cell function. ,similarity:Belongs to the interleukin-1 receptor family. ,similarity:Contains 1 TIR domain. ,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains. ,subunit:Interacts with MYD88 , IRAK1 , IRAK4 , and TRAF6. ,tissue specificity:Highly expressed in kidney , lung , placenta , stomach , skeletal muscle , colon and small intestine. Expression of isoform A is prevalent in the lung , testis , placenta , stomach and colon. However , isoform B is more abundant in the brain , kidney and the liver. Isoform C is not detected in brain , heart , liver , kidney and skeletal muscle. ,
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Function:
defense response , immune response , negative regulation of signal transduction , regulation of protein kinase cascade ,negative regulation of cell communication , negative regulation of protein kinase cascade , regulation of I-kappaB kinase/NF-kappaB cascade , negative regulation of I-kappaB kinase/NF-kappaB cascade , innate immune response ,
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Cellular Localization:
[Isoform C]: Cell membrane.; [Isoform B]: Secreted.; Cell membrane ; Single-pass type I membrane protein .
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Signaling Pathway
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Catalog: KE1248
Size
Price
Status
Qty.
5*96well
$1,850.00
2 weeks
0
2*96well
$740.00
2 weeks
0
96well
$370.00
2 weeks
0
Add to cart
Collected
Collect
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