Catalog: KE1245
Size
Price
Status
Qty.
5*96well
$1,850.00
2 weeks
0
2*96well
$740.00
2 weeks
0
96well
$370.00
2 weeks
0
Add to cart
Collected
Collect
Main Information
Reactivity
Human
Applications
ELISA
Conjugate/Modification
Unmodified
Detailed Information
Specificity
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Storage
2-8°C/6 months,Ship by ice bag
Modification
Unmodified
Sample Type
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Detection Method
Colorimetric
Sensitivity
63-4000 pg/mL.
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Antigen&Target Information
Specificity:
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
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Gene Name:
AGER
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Protein Name:
Advanced glycosylation end product-specific receptor
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Other Name:
AGER ;
RAGE ;
Advanced glycosylation end product-specific receptor ;
Receptor for advanced glycosylation end products
RAGE ;
Advanced glycosylation end product-specific receptor ;
Receptor for advanced glycosylation end products
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Background:
function:Mediates interactions of advanced glycosylation end products (AGE) . These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. Receptor for amyloid beta peptide. ,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain. ,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains. ,tissue specificity:Endothelial cells. ,
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Function:
defense response , inflammatory response , cell surface receptor linked signal transduction , intracellular signaling cascade , protein kinase cascade , JAK-STAT cascade , aging , positive regulation of cell proliferation , response to wounding , regulation of response to external stimulus , positive regulation of response to external stimulus , regulation of locomotion , positive regulation of locomotion , regulation of cell proliferation , positive regulation of behavior , positive regulation of response to stimulus , regulation of smooth muscle cell proliferation , positive regulation of smooth muscle cell proliferation , regulation of behavior , regulation of chemotaxis , positive regulation of chemotaxis , regulation of positive chemotaxis , positive regulation of positive chemotaxis , induction of positive chemotaxis ,
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Cellular Localization:
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.; [Isoform 10]: Cell membrane ; Single-pass type I membrane protein .
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Tissue Expression:
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Signaling Pathway
Reference Citation({{totalcount}})
Catalog: KE1245
Size
Price
Status
Qty.
5*96well
$1,850.00
2 weeks
0
2*96well
$740.00
2 weeks
0
96well
$370.00
2 weeks
0
Add to cart
Collected
Collect
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