Catalog: KA3879C
Size
Price
Status
Qty.
96well
$330.00
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0
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Main Information
Reactivity
Human
Applications
ELISA
Conjugate/Modification
Unmodified
Detailed Information
Storage
2-8°C/6 months
Modification
Unmodified
Detection Method
Colorimetric
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Antigen&Target Information
Gene Name:
ELAC2
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Other Name:
Zinc phosphodiesterase ELAC protein 2 ;
ElaC homolog protein 2 ;
Heredity prostate cancer protein 2 ;
Ribonuclease Z 2 ;
RNase Z 2 ;
tRNA 3 endonuclease 2 ;
tRNase Z 2 ;
ElaC homolog protein 2 ;
Heredity prostate cancer protein 2 ;
Ribonuclease Z 2 ;
RNase Z 2 ;
tRNA 3 endonuclease 2 ;
tRNase Z 2 ;
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Background:
catalytic activity:Endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.,cofactor:Zinc.,disease:Defects in ELAC2 are involved in prostate cancer (CaP) [MIM:176807].,function:Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.,similarity:Belongs to the RNase Z family.,subunit:Homodimer.,tissue specificity:Widely expressed. Highly expressed in heart, placenta, liver, skeletal muscle, kidney, pancreas, testis and ovary. Weakly expressed in brain, lung, spleen, thymus, prostate, small intestine, colon and leukocytes.,
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Function:
RNA processing, tRNA metabolic process, tRNA processing, ncRNA processing, ncRNA metabolic process,
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Cellular Localization:
Mitochondrion . Mitochondrion matrix, mitochondrion nucleoid . Nucleus . Mainly mitochondrial.
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Tissue Expression:
Widely expressed. Highly expressed in heart, placenta, liver, skeletal muscle, kidney, pancreas, testis and ovary. Weakly expressed in brain, lung, spleen, thymus, prostate, small intestine, colon and leukocytes.
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Reference Citation({{totalcount}})
Catalog: KA3879C
Size
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Status
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96well
$330.00
In stock
0
Add to cart
Collected
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