DUSP9

Dual specificity protein phosphatase 9 ;
EC 3.1.3.48 ;
Mitogen-activated protein kinase phosphatase 4 ;
MAP kinase phosphatase 4 ;
MKP-4 ;

catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,function:Inactivates MAP kinases. Has a specificity for the ERK family.,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.,similarity:Contains 1 rhodanese domain.,similarity:Contains 1 tyrosine-protein phosphatase domain.,

MAPKKK cascade, inactivation of MAPK activity, negative regulation of protein kinase activity, protein amino acid dephosphorylation, phosphorus metabolic process, phosphate metabolic process, intracellular signaling cascade,protein kinase cascade, JNK cascade, dephosphorylation, regulation of phosphate metabolic process, stress-activated protein kinase signaling pathway, cellular response to stress, negative regulation of kinase activity, regulation of phosphorylation, negative regulation of catalytic activity, regulation of MAP kinase activity, negative regulation of MAP kinase activity, regulation of kinase activity, negative regulation of molecular function, regulation of protein kinase activity, regulation of phosphorus metabolic process, regulation of transferase activity, negative regulation of transferase activity,

Cytoplasm.