Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

SPP1

Osteopontin

SPP1 ;
BNSP ;
OPN ;
PSEC0156 ;
Osteopontin ;
Bone sialoprotein 1 ;
Nephropontin ;
Secreted phosphoprotein 1 ;
SPP-1 ;
Urinary stone protein ;
Uropontin

disease:This protein plays a principal role in urinary stone formation as the stone matrix. ,function:Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity. ,function:Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. ,online information:Osteopontin entry ,PTM:Extensively phosphorylated on clustered serine residues. ,PTM:N- and O-glycosylated. ,similarity:Belongs to the osteopontin family. ,subunit:Ligand for integrin alpha-V/beta-3. ,

skeletal system development , ossification , regulation of cell growth , osteoblast differentiation , placenta development ,maternal placenta development , reproductive developmental process , defense response , inflammatory response , cell adhesion , female pregnancy , embryo implantation , response to nutrient , regulation of cell size , response to wounding ,response to endogenous stimulus , response to hormone stimulus , response to extracellular stimulus , response to organic substance , negative regulation of cell development , regulation of cell morphogenesis involved in differentiation , regulation of cell-substrate adhesion , positive regulation of cell-substrate adhesion , regulation of neuron projection development , negative regulation of neuron projection development , regulation of cell morphogenesis , biological adhesion , regulation of cell adhesion , negative regulation of cell growth , biomineral formation , regulation of cell projection organization , negative regulation of cell projection organization , response to nutrient levels , regulation of response to external stimulus , negative regulation of response to external stimulus ,regulation of cellular component size , regulation of homeostatic process , positive regulation of homeostatic process ,response to vitamin , response to vitamin D , regulation of tissue remodeling , positive regulation of tissue remodeling ,regulation of growth , regulation of bone resorption , negative regulation of cell differentiation , regulation of neuron differentiation , positive regulation of bone resorption , positive regulation of cell adhesion , negative regulation of cell size , negative regulation of growth , decidualization , regulation of bone remodeling , positive regulation of bone remodeling , response to steroid hormone stimulus , negative regulation of response to stimulus , regulation of developmental growth , negative regulation of developmental growth , regulation of collateral sprouting , negative regulation of collateral sprouting , regulation of axon regeneration , negative regulation of axon regeneration ,regulation of collateral sprouting of intact axon in response to injury , negative regulation of collateral sprouting of intact axon in response to injury , regulation of neurogenesis , negative regulation of neurogenesis , regulation of axonogenesis , negative regulation of axonogenesis , negative regulation of cellular component organization , positive regulation of multicellular organismal process , regulation of nervous system development , regulation of cell development , bone development , regulation of neuron projection regeneration , negative regulation of neuron projection regeneration , regulation of cellular response to stress ,

Secreted.