Catalog: KE1238
Size
Price
Status
Qty.
5*96well
$1,850.00
2 weeks
0
2*96well
$740.00
2 weeks
0
96well
$370.00
2 weeks
0
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Main Information
Reactivity
Human
Applications
ELISA
Conjugate/Modification
Unmodified
Detailed Information
Specificity
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Storage
2-8°C/6 months,Ship by ice bag
Modification
Unmodified
Sample Type
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Detection Method
Colorimetric
Sensitivity
63-4000 pg/ml
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Antigen&Target Information
Specificity:
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
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Gene Name:
MPO
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Protein Name:
Myeloperoxidase
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Other Name:
MPO ;
Myeloperoxidase ;
MPO
Myeloperoxidase ;
MPO
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Background:
catalytic activity:Cl (-) + H (2) O (2) = HOCl + 2 H (2) O. ,catalytic activity:Donor + H (2) O (2) = oxidized donor + 2 H (2) O. ,cofactor:Binds 1 calcium ion per heterodimer. ,cofactor:Binds 1 heme B (iron-protoporphyrin IX) group covalently per heterodimer. ,disease:Defects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis. ,function:Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN , MPO catalyzes the production of hypohalous acids , primarily hypochlorous acid in physiologic situations , and other toxic intermediates that greatly enhance PMN microbicidal activity. ,online information:MPO mutation db ,online information:Myeloperoxidase entry ,similarity:Belongs to the peroxidase family. XPO subfamily. ,subunit:Tetramer of two light chains and two heavy chains. ,
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Function:
response to reactive oxygen species , oxygen and reactive oxygen species metabolic process , anti-apoptosis , defense response , response to oxidative stress , response to inorganic substance , regulation of cell death , cellular response to stress , macromolecular complex remodeling , protein-lipid complex remodeling , plasma lipoprotein particle remodeling ,low-density lipoprotein particle remodeling , cellular response to oxidative stress , cellular response to reactive oxygen species , response to hydrogen peroxide , hydrogen peroxide metabolic process , hydrogen peroxide catabolic process ,regulation of apoptosis , negative regulation of apoptosis , regulation of programmed cell death , negative regulation of programmed cell death , macromolecular complex subunit organization , oxidation reduction , negative regulation of cell death , cellular response to hydrogen peroxide ,
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Cellular Localization:
Lysosome.
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Signaling Pathway
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Catalog: KE1238
Size
Price
Status
Qty.
5*96well
$1,850.00
2 weeks
0
2*96well
$740.00
2 weeks
0
96well
$370.00
2 weeks
0
Add to cart
Collected
Collect
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