Catalog: KE1215
Size
Price
Status
Qty.
5*96well
$1,850.00
2 weeks
0
2*96well
$740.00
2 weeks
0
96well
$370.00
2 weeks
0
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Collected
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Main Information
Reactivity
Human
Applications
ELISA
Conjugate/Modification
Unmodified
Detailed Information
Specificity
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Storage
2-8°C/6 months,Ship by ice bag
Modification
Unmodified
Sample Type
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Detection Method
Colorimetric
Sensitivity
625-20000 pg/ml
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RS0002
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Antigen&Target Information
Specificity:
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
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Gene Name:
CX3CL1
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Protein Name:
Fractalkine
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Other Name:
CX3CL1 ;
FKN ;
NTT ;
SCYD1 ;
A-152E5.2 ;
Fractalkine ;
C-X3-C motif chemokine 1 ;
CX3C membrane-anchored chemokine ;
Neurotactin ;
Small-inducible cytokine D1
FKN ;
NTT ;
SCYD1 ;
A-152E5.2 ;
Fractalkine ;
C-X3-C motif chemokine 1 ;
CX3C membrane-anchored chemokine ;
Neurotactin ;
Small-inducible cytokine D1
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Background:
function:The soluble form is chemotactic for T-cells and monocytes , but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1. ,induction:By TNF and IL-1 in pulmonary endothelial cells and umbilical vein endothelial cells. ,online information:CX3CL1 entry ,PTM:A soluble short 95 kDa form may be released by proteolytic cleavage from the long membrane-anchored form. ,similarity:Belongs to the intercrine delta family. ,subunit:Monomer. ,tissue specificity:Small intestine , colon , testis , prostate , heart , brain , lung , skeletal muscle , kidney and pancreas. ,
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Function:
cell activation , cell motion , chemotaxis , defense response , immune response , cell adhesion , behavior , locomotory behavior , cell migration , cytokine-mediated signaling pathway , regulation of cell-cell adhesion , positive regulation of cell-cell adhesion , biological adhesion , regulation of cell adhesion , leukocyte chemotaxis , positive regulation of defense response , regulation of response to external stimulus , positive regulation of response to external stimulus , taxis ,cellular extravasation , leukocyte activation , positive regulation of cell adhesion , positive regulation of response to stimulus , cell motility , regulation of inflammatory response , positive regulation of inflammatory response , leukocyte migration , leukocyte adhesive activation , regulation of calcium-independent cell-cell adhesion , positive regulation of calcium-independent cell-cell adhesion , localization of cell , cell chemotaxis ,
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Cellular Localization:
Cell membrane ; Single-pass type I membrane protein .; [Processed fractalkine]: Secreted .
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Signaling Pathway
Organismal Systems >> Immune system >> Chemokine signaling pathway
Environmental Information Processing >> Signal transduction >> TNF signaling pathway
Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction
Environmental Information Processing >> Signaling molecules and interaction >> Viral protein interaction with cytokine and cytokine receptor
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Catalog: KE1215
Size
Price
Status
Qty.
5*96well
$1,850.00
2 weeks
0
2*96well
$740.00
2 weeks
0
96well
$370.00
2 weeks
0
Add to cart
Collected
Collect
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