Catalog: KE1212
Size
Price
Status
Qty.
5*96well
$1,850.00
2 weeks
0
2*96well
$740.00
2 weeks
0
96well
$370.00
2 weeks
0
Add to cart
Collected
Collect
Main Information
Reactivity
Human
Applications
ELISA
Conjugate/Modification
Unmodified
Detailed Information
Specificity
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Storage
2-8°C/6 months,Ship by ice bag
Modification
Unmodified
Sample Type
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
Detection Method
Colorimetric
Sensitivity
32-2000 pg/ml
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Antigen&Target Information
Specificity:
Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
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Gene Name:
CFD
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Protein Name:
Complement factor D
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Other Name:
CFD ;
DF ;
PFD ;
Complement factor D ;
Adipsin ;
C3 convertase activator ;
Properdin factor D
DF ;
PFD ;
Complement factor D ;
Adipsin ;
C3 convertase activator ;
Properdin factor D
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Background:
catalytic activity:Selective cleavage of Arg-|-Lys bond in complement factor B when in complex with complement subcomponent C3b or with cobra venom factor. ,disease:Defects in CFD are the cause of complement factor D deficiency [MIM:134350]. This deficiency predisposes to invasive meningococcal disease. ,function:Factor D cleaves factor B when the latter is complexed with factor C3b , activating the C3bbb complex , which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. ,online information:CFD mutation db ,similarity:Belongs to the peptidase S1 family. ,similarity:Contains 1 peptidase S1 domain. ,
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Function:
immune effector process , activation of immune response , acute inflammatory response , activation of plasma proteins involved in acute inflammatory response , positive regulation of immune system process , proteolysis , defense response , inflammatory response , immune response , complement activation , complement activation , alternative pathway , humoral immune response , cell surface receptor linked signal transduction , Notch signaling pathway ,response to wounding , protein processing , innate immune response , positive regulation of response to stimulus ,positive regulation of immune response , protein maturation , protein maturation by peptide bond cleavage ,
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Cellular Localization:
Secreted.
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Reference Citation({{totalcount}})
Catalog: KE1212
Size
Price
Status
Qty.
5*96well
$1,850.00
2 weeks
0
2*96well
$740.00
2 weeks
0
96well
$370.00
2 weeks
0
Add to cart
Collected
Collect
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