AKAP1

A-kinase anchor protein 1, mitochondrial ;
A-kinase anchor protein 149 kDa ;
AKAP 149 ;
Dual specificity A-kinase-anchoring protein 1 ;
D-AKAP-1 ;
Protein kinase A-anchoring protein 1 ;
PRKA1 ;
Spermatid A-kinase anchor protein 84 ;
S-AKAP84 ;

domain:RII-alpha binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer.,function:Binds to type I and II regulatory subunits of protein kinase A and anchors them to the cytoplasmic face of the mitochondrial outer membrane.,similarity:Contains 1 KH domain.,similarity:Contains 1 Tudor domain.,tissue specificity:AKAP149 is highly expressed in prostate and small intestine whereas S-AKAP84 is expressed in kidney, pancreas, liver, lung and brain. AKAP149 is also expressed in colon carcinoma.,

Mitochondrion outer membrane . Mitochondrion .

Isoform 1 is detected in thymus, prostate, testis, ovary, colon and small intestine (PubMed:8769136). Isoform 2 is highly expressed in testis and detected at much lower levels in kidney, pancreas, liver, lung and brain (PubMed:7499250).